Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | SYK | P43405 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | FOS | P01100 | 1/20 | 0.54 |
| ▸ | JUN | P05412 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174009 | 0.89 | ALDH1A1 (0.76) | MAPTALDH1A1SMN1; SMN2SYKMAPK1 | |
| SCHEMBL5236888 | 0.87 | MAPT (0.69) | MAPTALDH1A1SMN1; SMN2SYKMAPK1 | |
| SCHEMBL1313596 | 0.86 | SYK (0.79) | MAPTALDH1A1SMN1; SMN2SYKMAPK1 | |
| SCHEMBL1774109 | 0.82 | ALDH1A1 (0.63) | MAPTALDH1A1SMN1; SMN2SYKMAPK1 | |
| SCHEMBL1814172 | 0.81 | MAPT (0.65) | MAPTALDH1A1SMN1; SMN2SYKMAPK1 | |
| SCHEMBL4854253 | 0.81 | HTT (0.72) | MAPTALDH1A1SMN1; SMN2SYKMAPK1 | |
| SCHEMBL1773964 | 0.81 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2SYKMAPK1 | |
| SCHEMBL1774892 | 0.81 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2SYKMAPK1 | |
| SCHEMBL29545771 | 0.80 | ALDH1A1 (0.70) | MAPTALDH1A1SMN1; SMN2SYKMAPK1 | |
| SCHEMBL1521842 | 0.80 | ALDH1A1 (0.70) | MAPTALDH1A1SMN1; SMN2SYKMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009033183-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF HCV AND CONDITIONS ASSOCIATED WITH CD81 BINDING | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2009-03-12 | — | — | WO | disclosed |
| WO-2009033183-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF HCV AND CONDITIONS ASSOCIATED WITH CD81 BINDING | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2009-03-12 | — | — | WO | disclosed |