Sugi Predict

Sugi Predict / Compounds / SCHEMBL3848692

SCHEMBL3848692

SCHEMBL3848692

CCc1cc(Sc2ccc(N)c(CC)c2)ccc1N

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.65
▸ ALDH1A1 P00352 3/20 0.65
▸ POLB P06746 3/20 0.65
▸ MAPK1 P28482 3/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ HTT P42858 2/20 0.37
▸ KMT2A Q03164 4/20 0.34
▸ MEN1 O00255 3/20 0.34
▸ ANXA2 P07355 1/20 0.34
▸ S100A10 P60903 1/20 0.34
▸ KDM4E B2RXH2 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ PKM P14618 1/20 0.33
▸ MCL1 Q07820 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ NPC1 O15118 1/20 0.32
▸ APOBEC3G Q9HC16 1/20 0.32
▸ PDE7A Q13946 1/20 0.32
▸ GCK P35557 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31457297 0.92 MAPT (0.57) MAPTALDH1A1POLBMAPK1CYP3A4
SCHEMBL11803703 0.87 ALDH1A1 (0.65) MAPTALDH1A1POLBMAPK1CYP3A4
SCHEMBL10570644 0.85 ALDH1A1 (0.62) MAPTALDH1A1POLBTSHRHTT
SCHEMBL11375649 0.84 ALDH1A1 (0.53) MAPTALDH1A1POLBMAPK1CYP3A4
SCHEMBL434002 0.83 MAPT (0.47) MAPTALDH1A1POLBMAPK1CYP3A4
SCHEMBL9700714 0.83 MAPT (0.61) MAPTALDH1A1POLBMAPK1HTT
SCHEMBL31558890 0.83 MAPT (0.47) MAPTALDH1A1POLBMAPK1CYP3A4
SCHEMBL5381291 0.82 ALDH1A1 (0.59) MAPTALDH1A1POLBMAPK1HTT
SCHEMBL5377030 0.80 MAPT (0.45) MAPTALDH1A1POLBMAPK1CYP3A4
SCHEMBL5379527 0.79 MAPT (0.44) MAPTALDH1A1POLBCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555479-A Nonwoven abrasive article with wax antiloading compound and method of using the same 3M INNOVATIVE PROPERTIES CO 2016-05-04 — — CN disclosed
US-8501874-B2 Thermosetting resin composition, multilayer body using same, and circuit board KANEKA CORPORATION (JP) 2013-08-06 — — US disclosed
US-7521511-B2 Thermosetting resin composition, multilayer body using same, and circuit board KANEKA CORPORATION (JP) 2009-04-21 — — US disclosed
US-20080306220-A1 Thermosetting Resin Composition, Multilayer Body Using Same, and Circuit Board KANEKA CORPORATION (JP) 2008-12-11 — — US disclosed
US-7202359-B2 Azaoxa heterocyclic compound and method of preparing the same CHANG CHUN PLASTICS CO., LTD. (TW) 2007-04-10 — — US disclosed
US-20060205891-A1 Thermosetting resin composition, multilayer body using same, and circuit board KANEKA CORPORATION (JP) 2006-09-14 — — US disclosed
CN-1234706-C Nitrogen-oxygen heterocyclic compound and preparation method thereof CHANGCHUN ARTIFICIAL RESIN FAC (CN) 2006-01-04 — — CN disclosed
US-20050085634-A1 Azaoxa heterocyclic compound and method of preparing the same CHANG CHUN PLASTICS CO., LTD. (TW) 2005-04-21 — — US disclosed
CN-1490318-A Nitrogen-oxygen heterocyclic compound and preparation method thereof 长春人造树脂厂股份有限公司 2004-04-21 — — CN disclosed
US-20040068084-A1 Azaoxa heterocyclic compound and method of preparing the same CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-08 — — US disclosed
US-4075171-A CURING BY COUPLING UNIVERSITY OF NOTRE DAME DU LAC (US) 1978-02-21 — — US disclosed
US-4060515-A Chain-extending nitrile end-capped polyimides UNIVERSITY OF NOTRE DAME DU LAC (US) 1977-11-29 — — US disclosed
US-4058505-A Chain-extending amine end-capped polyimides UNIVERSITY OF NOTRE DAME DU LAC (US) 1977-11-15 — — US disclosed
US-4055543-A Chain-extending Schiff base terminated polyimides and method of preparation ALELIO GAETANO FRANCIS D 1977-10-25 — — US disclosed
US-4026871-A Chain-extending phenolic end-capped polyimides UNIVERSITY OF NOTRE DAME (US) 1977-05-31 — — US disclosed
US-4026833-A CROSSLINKED FOAMS UNIVERSITY OF NOTRE DAME (US) 1977-05-31 — — US disclosed
US-4026904-A Aromatic epoxy-terminated polyimides UNIVERSITY OF NOTRE DAME (US) 1977-05-31 — — US disclosed
US-3998786-A USEFUL FOR PREPARING COATINGS UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-21 — — US disclosed
US-3996196-A Polyimide-metallo-phthalocyanines and their preparation UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-07 — — US disclosed
US-3987003-A THERMALLY STABLE DIOXO AND DITHIO-BENZISOQUINOLINE COMPOSITIONS AND PROCESS OF SYNTHESIZING SAME THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1976-10-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040068084-A1 Azaoxa heterocyclic compound and method of preparing the same AOX1, KDM1A, BMI1 MAPT 2811/4885ALDH1A1 81/4885POLB 1238/4885
US-20050085634-A1 Azaoxa heterocyclic compound and method of preparing the same AOX1, KDM1A, BMI1 MAPT 2734/4885ALDH1A1 116/4885POLB 1310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.