Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11803703 | 0.83 | ALDH1A1 (0.65) | MAPTALDH1A1POLBMCL1BCL2A1 | |
| SCHEMBL3848692 | 0.83 | MAPT (0.65) | MAPTALDH1A1POLBMCL1HTT | |
| SCHEMBL10570644 | 0.82 | ALDH1A1 (0.62) | MAPTALDH1A1POLBMCL1HTT | |
| SCHEMBL5381291 | 0.78 | ALDH1A1 (0.59) | MAPTALDH1A1POLBHTTMEN1 | |
| SCHEMBL31457297 | 0.77 | MAPT (0.57) | MAPTALDH1A1POLBMCL1HTT | |
| SCHEMBL8512890 | 0.73 | CA12 (0.47) | MAPTALDH1A1POLBMCL1BCL2A1 | |
| SCHEMBL29487551 | 0.73 | CA12 (0.47) | MAPTALDH1A1POLBMCL1BCL2A1 | |
| SCHEMBL11375649 | 0.73 | ALDH1A1 (0.53) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL237448 | 0.72 | ALDH1A1 (0.50) | MAPTALDH1A1POLBCA2HTT | |
| SCHEMBL11835307 | 0.72 | MCL1 (0.38) | MAPTALDH1A1POLBMCL1BCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106943-A | Molding materials; blend of trimer of polyisocyanate, epoxy compounds, and aromatic polyamine | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0421393-A2 | Resin, compositions, shaped articles, and methods for manufacture | Takeda Chemical Industries, Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |