Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | S100B | P04271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434003 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL5377909 | 0.82 | MAPT (0.41) | ALDH1A1MAPTPOLBHTTMEN1 | |
| SCHEMBL11803703 | 0.82 | ALDH1A1 (0.65) | ALDH1A1MAPTPOLBHTTMEN1 | |
| SCHEMBL3848692 | 0.82 | MAPT (0.65) | ALDH1A1MAPTPOLBHTTMEN1 | |
| SCHEMBL5379533 | 0.81 | MAPT (0.41) | ALDH1A1MAPTPOLBHTTMEN1 | |
| SCHEMBL10570644 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MAPTPOLBHTTMEN1 | |
| SCHEMBL5381223 | 0.80 | ALOX5 (0.41) | ALDH1A1MAPTPOLBHTTMEN1 | |
| SCHEMBL9700714 | 0.78 | MAPT (0.61) | ALDH1A1MAPTPOLBHTTMEN1 | |
| SCHEMBL5397993 | 0.78 | HTT (0.44) | ALDH1A1MAPTPOLBHTT | |
| SCHEMBL27885463 | 0.77 | ESR1 (0.47) | ALDH1A1MAPTPOLBHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555479-A | Nonwoven abrasive article with wax antiloading compound and method of using the same | 3M INNOVATIVE PROPERTIES CO | 2016-05-04 | — | — | CN | disclosed |
| US-7202359-B2 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2007-04-10 | — | — | US | disclosed |
| CN-1234706-C | Nitrogen-oxygen heterocyclic compound and preparation method thereof | CHANGCHUN ARTIFICIAL RESIN FAC (CN) | 2006-01-04 | — | — | CN | disclosed |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2005-04-21 | — | — | US | disclosed |
| CN-1490318-A | Nitrogen-oxygen heterocyclic compound and preparation method thereof | 长春人造树脂厂股份有限公司 | 2004-04-21 | — | — | CN | disclosed |
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | ALDH1A1 81/4885MAPT 2811/4885POLB 1238/4885 |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | ALDH1A1 116/4885MAPT 2734/4885POLB 1310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.