Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3828851 | 0.91 | RAB9A (0.55) | RAB9AKMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL3826601 | 0.84 | RAB9A (0.48) | RAB9AKMT2AKDM4EHTR1ADRD2 | |
| SCHEMBL3825171 | 0.84 | RAB9A (0.53) | RAB9AKMT2ASMN1; SMN2L3MBTL1HTR1A | |
| Hydrochloric Acid SCHEMBL3822406 | 0.84 | RAB9A (0.52) | RAB9AKMT2ASMN1; SMN2L3MBTL1HTR1A | |
| SCHEMBL3823150 | 0.84 | ME2 (0.42) | RAB9AKDM4ESMN1; SMN2L3MBTL1HTR1A | |
| SCHEMBL8179037 | 0.83 | L3MBTL1 (0.54) | RAB9AMAPTKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL8177578 | 0.82 | OPRM1 (0.45) | RAB9AKDM4ESMN1; SMN2L3MBTL1HTR1A | |
| SCHEMBL3830607 | 0.82 | TACR3 (0.46) | RAB9AHTR1ADRD2DRD4HTR2A | |
| SCHEMBL3826502 | 0.81 | RAB9A (0.45) | RAB9AKMT2AHTR1ADRD2DRD4 | |
| SCHEMBL3842981 | 0.81 | SMN1; SMN2 (0.48) | RAB9AMAPTKDM4ESMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091917-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-08-26 | — | — | EP | claimed |
| WO-2008073934-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |