Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.87 |
| ▸ | RBP4 | P02753 | 7/20 | 0.87 |
| ▸ | MAPT | P10636 | 5/20 | 0.87 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.87 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.87 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.87 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.87 |
| ▸ | BLM | P54132 | 3/20 | 0.87 |
| ▸ | LMNA | P02545 | 3/20 | 0.87 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.87 |
| ▸ | MEN1 | O00255 | 2/20 | 0.87 |
| ▸ | GMNN | O75496 | 2/20 | 0.87 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.87 |
| ▸ | MTOR | P42345 | 2/20 | 0.87 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.87 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.87 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.87 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15701491 | 0.94 | ALDH1A1 (0.87) | ALDH1A1RBP4MAPTCYP3A4HIF1A | |
| SCHEMBL12388931 | 0.94 | ALDH1A1 (0.87) | ALDH1A1RBP4MAPTCYP3A4HIF1A | |
| Fenretinide SCHEMBL13402304 | 0.93 | RBP4 (1.00) | ALDH1A1RBP4MAPTCYP3A4HIF1A | |
| Fenretinide SCHEMBL11703 | 0.93 | RBP4 (1.00) | ALDH1A1RBP4MAPTCYP3A4HIF1A | |
| Fenretinide SCHEMBL15703189 | 0.93 | RBP4 (1.00) | ALDH1A1RBP4MAPTCYP3A4HIF1A | |
| Fenretinide SCHEMBL9838209 | 0.93 | RBP4 (1.00) | ALDH1A1RBP4MAPTCYP3A4HIF1A | |
| Fenretinide SCHEMBL10629371 | 0.93 | RBP4 (1.00) | ALDH1A1RBP4MAPTCYP3A4HIF1A | |
| Fenretinide SCHEMBL4874840 | 0.93 | RBP4 (1.00) | ALDH1A1RBP4MAPTCYP3A4HIF1A | |
| Fenretinide SCHEMBL19121 | 0.93 | RBP4 (1.00) | ALDH1A1RBP4MAPTCYP3A4HIF1A | |
| Fenretinide SCHEMBL11704 | 0.93 | RBP4 (1.00) | ALDH1A1RBP4MAPTCYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550510-B2 | Solid phase synthesis of arylretinamides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-06-23 | — | — | US | disclosed |
| US-20040102650-A1 | Solid phase synthesis of arylretinamides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-05-27 | — | — | US | disclosed |
| US-6696606-B2 | REACTING HEXACHLOROACETONE WITH TRIPHENYLPHOSPHINE; CHLORINATION OF RETINOIC ACID; THEN AROMATIC AMINE; ANTICANCER AGENTS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION | 2004-02-24 | — | — | US | disclosed |
| US-20030105164-A1 | Solid phase synthesis of arylretinamides | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2003-06-05 | — | — | US | disclosed |
| WO-2003003987-A2 | SOLID PHASE SYNTHESIS OF ARYLRETINAMIDES | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102650-A1 | Solid phase synthesis of arylretinamides | RARA, LRAT, NR2E3 | ALDH1A1 1637/4885RBP4 14/4885MAPT 4705/4885 |
| US-20030105164-A1 | Solid phase synthesis of arylretinamides | RARA, LRAT, NR2E3 | ALDH1A1 1637/4885RBP4 14/4885MAPT 4705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.