Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 6/20 | 0.58 |
| ▸ | CA1 | P00915 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | PLEC | Q15149 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-(Benzylideneamino)Phenol SCHEMBL1877533 | 0.91 | S100B (0.71) | S100BCA2CA1L3MBTL1ALDH1A1 | |
| 4-(Benzylideneamino)Phenol SCHEMBL1877535 | 0.91 | S100B (0.71) | S100BCA2CA1L3MBTL1ALDH1A1 | |
| SCHEMBL2311083 | 0.91 | S100B (0.71) | S100BCA2CA1L3MBTL1ALDH1A1 | |
| SCHEMBL2311078 | 0.91 | S100B (0.71) | S100BCA2CA1L3MBTL1ALDH1A1 | |
| SCHEMBL13084384 | 0.89 | ALDH1A1 (0.63) | S100BCA2CA1L3MBTL1ALDH1A1 | |
| SCHEMBL60000 | 0.89 | ALDH1A1 (0.63) | S100BCA2CA1L3MBTL1ALDH1A1 | |
| SCHEMBL59999 | 0.89 | ALDH1A1 (0.63) | S100BCA2CA1L3MBTL1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL2273341 | 0.86 | ALDH1A1 (0.61) | S100BCA2CA1L3MBTL1ALDH1A1 | |
| SCHEMBL22577661 | 0.86 | ALDH1A1 (0.61) | S100BCA2CA1L3MBTL1ALDH1A1 | |
| SCHEMBL340770 | 0.86 | ALDH1A1 (0.61) | S100BCA2CA1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114988992-B | Method for preparing propanal by hydroformylation of dry gas ethylene | 中海油天津化工研究设计院有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-114870901-B | Bisphosphite polymer catalyst for olefin hydroformylation, preparation method and application thereof | 中国海洋石油集团有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-114988992-A | Method for preparing propionaldehyde by dry gas ethylene hydroformylation | 中海油天津化工研究设计院有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-114870901-A | Bisphosphite polymer catalyst for olefin hydroformylation and preparation method and application thereof | 中国海洋石油集团有限公司 | 2022-08-09 | — | — | CN | disclosed |
| EP-3921324-A1 | INHIBITORS OF ADENYLATE-FORMING ENZYME MENE | Memorial Sloan Kettering Cancer Center (US) | 2021-12-15 | — | — | EP | disclosed |
| WO-2020163673-A1 | INHIBITORS OF ADENYLATE-FORMING ENZYME MENE | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-08-13 | — | — | WO | disclosed |
| US-20090275598-A1 | Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders | AMGEN INC. (US) | 2009-11-05 | — | — | US | disclosed |
| US-7582803-B2 | Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders | AMGEN INC. (US) | 2009-09-01 | — | — | US | disclosed |
| EP-1924546-A1 | CONFORMATIONALLY CONSTRAINED 3- (4-HYDROXY-PHENYL) - SUBSTITUTED-PROPANOIC ACIDS USEFUL FOR TREATING METABOLIC DISORDERS | Amgen, Inc (US) | 2008-05-28 | — | — | EP | disclosed |
| US-20070066647-A1 | Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders | AMGEN ING. (US) | 2007-03-22 | — | — | US | disclosed |
| WO-2007033002-A1 | CONFORMATIONALLY CONSTRAINED 3- (4-HYDROXY-PHENYL) - SUBSTITUTED-PROPANOIC ACIDS USEFUL FOR TREATING METABOLIC DISORDERS | AMGEN INC. (US) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066647-A1 | Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders | PC, PNLIP, PDHX | S100B 4478/4885CA2 671/4885CA1 1973/4885 |
| US-20090275598-A1 | Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders | PC, PNLIP, PDHX | S100B 4478/4885CA2 671/4885CA1 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.