Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10602875 | 0.87 | PTK2B (0.70) | PTK2BESR1ESR2NPSR1MAPT | |
| SCHEMBL8204774 | 0.81 | HPGD (0.67) | PTK2BESR1ESR2NPSR1MAPT | |
| SCHEMBL5705992 | 0.79 | PTK2B (0.60) | PTK2BESR1ESR2NPSR1MAPT | |
| SCHEMBL5706098 | 0.77 | SLC6A3 (0.64) | PTK2BESR1ESR2NPSR1MAPT | |
| SCHEMBL11228704 | 0.77 | PTK2B (0.57) | PTK2BESR1ESR2NPSR1MAPT | |
| SCHEMBL27450690 | 0.77 | KMT2A (0.69) | PTK2BESR1ESR2NPSR1MAPT | |
| SCHEMBL5706131 | 0.76 | TSHR (0.66) | PTK2BESR1ESR2NPSR1MAPT | |
| SCHEMBL5706021 | 0.74 | SLC6A3 (0.60) | PTK2BESR1ESR2NPSR1MAPT | |
| SCHEMBL5706002 | 0.74 | KMT2A (0.63) | PTK2BESR1ESR2NPSR1MAPT | |
| SCHEMBL3855988 | 0.74 | HSD17B10 (0.63) | PTK2BNPSR1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730228-B1 | NANO-COMPOSITE AND METHOD THEREOF | BRIDGESTONE CORP (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-7579398-B2 | Nano-composite and compositions therefrom | BRIDGESTONE CORPORATION (JP) | 2009-08-25 | — | — | US | disclosed |
| US-7572855-B2 | Nano-composite and compositions manufactured thereof | BRIDGESTONE CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20090182087-A1 | NANO-COMPOSITE AND COMPOSITIONS THEREFROM | BRIDGESTONE CORPORATION (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1730228-A1 | NANO-COMPOSITE AND METHOD THEREOF | Bridgestone Corporation (JP) | 2006-12-13 | — | — | EP | disclosed |
| US-20060173115-A1 | Nano-composite and compositions manufactured thereof | BRIDGESTONE CORPORATION (JP) | 2006-08-03 | — | — | US | disclosed |
| WO-2005095506-A1 | NANO-COMPOSITE AND METHOD THEREOF | BRIDGESTONE CORPORATION (JP) | 2005-10-13 | — | — | WO | disclosed |