SCHEMBL8204774

SCHEMBL8204774

O=C(Oc1ccccc1Cl)c1ccccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.67
HSD17B10 Q99714 3/20 0.67
ALDH1A1 P00352 3/20 0.67
KDM4E B2RXH2 2/20 0.67
ESR1 P03372 4/20 0.65
ESR2 Q92731 4/20 0.65
PTK2B Q14289 1/20 0.62
ALOX15 P16050 1/20 0.58
KMT2A Q03164 3/20 0.53
POLB P06746 1/20 0.53
GAA P10253 1/20 0.53
LMNA P02545 2/20 0.52
TSHR P16473 1/20 0.52
NPSR1 Q6W5P4 1/20 0.51
MEN1 O00255 1/20 0.49
TDP1 Q9NUW8 2/20 0.47
MAPT P10636 1/20 0.47
HTT P42858 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TP53 P04637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10602875 0.89 PTK2B (0.70) HPGDHSD17B10ALDH1A1KDM4EESR1
SCHEMBL10785217 0.88 ESR1 (0.64) HPGDHSD17B10ALDH1A1KDM4EESR1
SCHEMBL3635482 0.85 HPGD (0.76) HPGDHSD17B10ALDH1A1KDM4EESR1
SCHEMBL8210159 0.83 ESR1 (0.58) HPGDHSD17B10ALDH1A1KDM4EESR1
SCHEMBL8209348 0.82 HPGD (0.58) HPGDHSD17B10ALDH1A1KDM4EESR1
SCHEMBL10686808 0.81 HSD17B10 (0.71) HPGDHSD17B10ALDH1A1KDM4EESR1
SCHEMBL4182986 0.81 ESR1 (0.56) HPGDHSD17B10ALDH1A1KDM4EESR1
SCHEMBL5705992 0.81 PTK2B (0.60) HPGDHSD17B10ALDH1A1KDM4EESR1
SCHEMBL3852974 0.81 PTK2B (0.60) HPGDHSD17B10ALDH1A1KDM4EESR1
SCHEMBL22090079 0.80 ESR1 (0.67) HPGDHSD17B10ALDH1A1KDM4EESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4513052-A LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND RICOH CO., LTD. (JP) 1985-04-23 US claimed
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
EP-0090510-B1 O-CARBAMOYL SALICYLATES AND THEIR PREPARATION Council of Scientific and Industrial Research (IN) 1987-11-11 EP disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4513052-A LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND RICOH CO., LTD. (JP) 1985-04-23 US disclosed
EP-0090510-A2 O-carbamoyl salicylates and their preparation Council of Scientific and Industrial Research (IN) 1983-10-05 EP disclosed