Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.57 |
| ▸ | FEN1 | P39748 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | FES | P07332 | 1/20 | 0.52 |
| ▸ | FER | P16591 | 1/20 | 0.52 |
| ▸ | MARK3 | P27448 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.52 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.52 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.52 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6698432 | 0.96 | ALOX5AP (0.58) | ALOX5APFEN1ALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL15924549 | 0.85 | ALOX5AP (0.44) | ALOX5APFEN1ALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL6904423 | 0.85 | OPRM1 (0.58) | ALOX5APFEN1ALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL10782653 | 0.85 | ALOX5AP (0.44) | ALOX5APFEN1ALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL3853249 | 0.83 | MCOLN3 (0.57) | ALOX5APFEN1HTTPTGS2OPRM1 | |
| SCHEMBL31092638 | 0.83 | ALDH1A1 (0.51) | ALOX5APFEN1ALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL10957993 | 0.82 | SMN1; SMN2 (0.46) | ALOX5APFEN1ALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL30455565 | 0.80 | ALOX5AP (0.54) | ALOX5APFEN1ALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL20542378 | 0.79 | MCL1 (0.49) | ALOX5APFEN1ALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL9307372 | 0.79 | ALOX5AP (0.52) | ALOX5APFEN1ALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502533-A | Benzenesulfonamide derivatives and use thereof | 2692372安大略公司 | 2022-05-13 | — | — | CN | disclosed |
| US-20200131335-A1 | SURFACE ACTIVE ADJUVANT | RHODIA OPERATIONS (FR) | 2020-04-30 | — | — | US | disclosed |
| EP-3612604-A1 | SURFACE ACTIVE ADJUVANT | Rhodia Operations (FR) | 2020-02-26 | — | — | EP | disclosed |
| EP-3495359-A1 | FLAP MODULATORS | Janssen Pharmaceutica NV (BE) | 2019-06-12 | — | — | EP | disclosed |
| WO-2018193009-A1 | SURFACE ACTIVE ADJUVANT | RHODIA OPERATIONS (FR) | 2018-10-25 | — | — | WO | disclosed |
| US-5328884-A | Salicylic acid salt,and amide or sulfonamide as developer | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| US-5250108-A | Mixture of salicylic acid salt, amide and sulfonamide compounds | KANZAKI PAPER MANUFACTURING CO. LTD. (JP) | 1993-10-05 | — | — | US | disclosed |