Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL7639229 | 0.97 | GABRA1 (0.31) | GABRA1GABRB2FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL3268925 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL8631922 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8604940 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7929727 | 0.81 | FAAH (0.32) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL8635937 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL4078649 | 0.79 | — | — | |
| Fluoride Ion SCHEMBL7642939 | 0.78 | FAAH (0.32) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL8630901 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL672606 | 0.75 | FAAH (0.30) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |
| EP-1058694-B1 | Catalyst system, method for its production and its use for the polymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2003-04-09 | — | — | EP | claimed |
| US-6482902-B1 | Catalyst system | TARGOR GMBH (DE) | 2002-11-19 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6391989-B1 | COORDINATION CATALYST ON SUPPORT; POLYMERIZATION OF ALPHA-OLEFINS | BASELL POLYPROPYLEN GMBH (DE) | 2002-05-21 | — | — | US | claimed |
| US-6124231-A | Supported catalyst system, processes for its preparation, and its use for the polymerization of olefins | TARGOR GMBH (DE) | 2000-09-26 | — | — | US | claimed |
| EP-0545303-B1 | Process for preparing high molecular weight polyolefins | HOECHST AG (DE) | 1997-10-01 | — | — | EP | claimed |
| EP-1648946-B1 | OLEFIN POLYMERIZATION PROCESS | BASELL POLYOLEFINE GMBH (DE) | 2015-07-15 | — | — | EP | disclosed |
| US-8383731-B2 | Polypropylene-based adhesive compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-02-26 | — | — | US | disclosed |
| US-8101695-B2 | Propylene based terpolymers | BASELL POLYOLEFINE GMBH (DE) | 2012-01-24 | — | — | US | disclosed |
| US-8058350-B2 | Polypropylene composition | Basell Poliolefine Italia, s.r.l. (IT) | 2011-11-15 | — | — | US | disclosed |
| EP-1680468-B1 | POLYPROPYLENE COMPOSITION | BASELL POLIOLEFINE SRL (IT) | 2011-08-17 | — | — | EP | disclosed |
| US-7799722-B2 | Catalyst system for the polymerization of olefin | BASELL POLYOLEFINE GMBH (DE) | 2010-09-21 | — | — | US | disclosed |
| US-5770752-A | Process for reducing the concentration of by-products in product mixtures | TARGOR GMBH (DE) | 1998-06-23 | — | — | US | disclosed |
| US-5703149-A | Process for the preparation of stabilized olefin polymers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0567952-B1 | Olefin polymerization catalyst, process for its preparation, and its use | HOECHST AG (DE) | 1997-12-03 | — | — | EP | disclosed |
| US-5614455-A | Olefin polymerization catalyst, process for its preparation, and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-25 | — | — | US | disclosed |
| US-5578537-A | Olefin polymerization catalyst process for its preparation and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| EP-0578838-A1 | Olefin polymerization catalyst, process for its preparation, and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0567952-A1 | Olefin polymerization catalyst, process for its preparation, and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |