Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL385357 | 0.79 | GABRA1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL8631922 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL3268925 | 0.76 | — | — | |
| Fluoride Ion SCHEMBL7639229 | 0.76 | GABRA1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL8635937 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL9421533 | 0.72 | GABRA1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL2534898 | 0.72 | GABRA1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL9069654 | 0.71 | — | — | |
| SCHEMBL8506274 | 0.70 | GABRA1 (0.35) | — | |
| Propane SCHEMBL8628910 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545303-B1 | Process for preparing high molecular weight polyolefins | HOECHST AG (DE) | 1997-10-01 | — | — | EP | claimed |
| US-8383731-B2 | Polypropylene-based adhesive compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-02-26 | — | — | US | disclosed |
| US-20090156729-A1 | Polypropylene-Based Adhesive Compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2009-06-18 | — | — | US | disclosed |
| US-7521507-B2 | Polypropylene-based adhesive compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-7235618-B2 | Using an organometallic catalyst and chain transfer agents | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-06-26 | — | — | US | disclosed |
| US-7098277-B2 | Polypropylene films | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-08-29 | — | — | US | disclosed |
| US-7081299-B2 | Polypropylene fibers and fabrics | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-07-25 | — | — | US | disclosed |
| US-6846770-B2 | Highly active supported catalyst compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-01-25 | — | — | US | disclosed |
| US-20040028903-A1 | Polypropylene fibers and fabrics | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-02-12 | — | — | US | disclosed |
| US-6524988-B2 | Metallocene, an activator and a fluorided support; polymerization catalyst | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-02-25 | — | — | US | disclosed |
| US-20020123582-A1 | Highly active supported catalyst compositions | SPECA ANTHONY N (US) | 2002-09-05 | — | — | US | disclosed |
| US-6368999-B1 | METALLOCENE POLYEMRIZATION CATALYST, ACTIVATOR, AND A SUPPORT THAT HAS BEEN FLUORIDED USING A FLUORIDE CONTAINING COMPOUND, REACTIVE FUNCTIONALITIES OF THE SUPPORT ARE REDUCED AND/OR DEACTIVATED | EXXON MOBIL CHEMICAL PATENTS INC. | 2002-04-09 | — | — | US | disclosed |
| US-20010051698-A1 | Highly active supported catalyst compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-12-13 | — | — | US | disclosed |
| US-6306960-B1 | AUTOMOBILES, ORGANOLEPTIC USES | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-10-23 | — | — | US | disclosed |