Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656857 | 0.87 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL8068413 | 0.87 | ALDH1A1 (0.91) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL7629952 | 0.85 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL15049827 | 0.85 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL13630658 | 0.85 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL16350574 | 0.82 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL8106845 | 0.81 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL316404 | 0.79 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL13228838 | 0.79 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL568962 | 0.78 | ALDH1A1 (0.73) | ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2677990-B1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULFIDE/THIOL FUNCTION, A SPARINGLY OR NON-ETHOXYLATED FATTY ALCOHOL, A CATIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | OREAL (FR) | 2019-05-15 | — | — | EP | claimed |
| EP-2677996-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'ORÉAL (FR) | 2017-11-29 | — | — | EP | claimed |
| US-20140075687-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'OREAL (FR) | 2014-03-20 | — | — | US | claimed |
| EP-1671622-B2 | Hair protein assay method | OREAL (FR) | 2013-04-10 | — | — | EP | claimed |
| WO-2012113720-A2 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'OREAL (FR) | 2012-08-30 | — | — | WO | claimed |
| EP-1671622-B1 | Hair protein assay method | OREAL (FR) | 2009-04-08 | — | — | EP | claimed |
| US-20060140893-A1 | Assay of hair proteins | L'OREAL (FR) | 2006-06-29 | — | — | US | claimed |
| EP-0514282-B1 | Alkylamino mercaptoalkylamides or salts thereof acceptable for cosmetic use, their use as a reducing agent and a process for the permanent deformation of hair | OREAL (FR) | 1996-04-10 | — | — | EP | claimed |
| EP-0577473-B1 | Reducing cosmetic composition for the permanent deformation of hair based on a mercaptoalkylamino-amide and process for the permanent deformation of hair | OREAL (FR) | 1995-12-20 | — | — | EP | claimed |
| EP-2677996-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'ORÉAL (FR) | 2017-11-29 | — | — | EP | disclosed |
| US-9522106-B2 | Composition for dyeing keratinous fibres comprising a direct dye having a disulphide/thiol functional group, a thickening polymer, an ethoxylated fatty alcohol and/or a nonionic surfactant, an alkaline agent and a reducing agent | L'OREAL (FR) | 2016-12-20 | — | — | US | disclosed |
| US-20140075687-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'OREAL (FR) | 2014-03-20 | — | — | US | disclosed |
| WO-2012113720-A2 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'OREAL (FR) | 2012-08-30 | — | — | WO | disclosed |
| US-20060140893-A1 | Assay of hair proteins | L'OREAL (FR) | 2006-06-29 | — | — | US | disclosed |
| US-20050008666-A1 | Extracts of nonfruiting nonphotosynthetic filamentous bacteria for strengthening keratin materials | L'OREAL (FR) | 2005-01-13 | — | — | US | disclosed |
| US-5989534-A | Process for the permanent deformation of keratinous matter | L'OREAL (FR) | 1999-11-23 | — | — | US | disclosed |
| US-5833966-A | APPLYING AQUEOUS MIXTURE OF CARBOXYLIC ACID, ALKALINIZING AMINO COMPOUND AND HYDROGEN PEROXIDE AS OXIDIZER; FOR SOFTNESS, NO SENSITIZATION TO HAIR DYES | L'OREAL (FR) | 1998-11-10 | — | — | US | disclosed |
| US-5803095-A | Permanent wave compositions comprising substance P/CGRP antagonists | SOCIETE L'OREAL S.A. (FR) | 1998-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140075687-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | KRT18, ESD, ADH5 | ALDH1A1 97/4885SMN1; SMN2 4799/4885LMNA 1408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.