Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.71 |
| ▸ | TUBB | P07437 | 5/20 | 0.71 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.71 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.71 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.71 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.71 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.71 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.71 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.71 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.71 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.71 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.71 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.71 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.71 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.71 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | KIF11 | P52732 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906447 | 0.94 | TUBB4A (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10443772 | 0.82 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3858085 | 0.82 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3852376 | 0.79 | PPARG (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1505830 | 0.79 | MDM4 (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15563263 | 0.78 | PTGS2 (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7231679 | 0.77 | PPARG (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1460051 | 0.76 | F2 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28906377 | 0.76 | PTGS2 (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7650562 | 0.75 | HTR2A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | TUBB4A 614/4885TUBB 763/4885TUBA3C 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.