Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3847525 | 0.89 | PTGER1 (0.48) | PTGER1 | |
| SCHEMBL3854464 | 0.86 | PTGER1 (0.42) | PTGER1 | |
| SCHEMBL3856745 | 0.84 | PTGER1 (0.49) | PTGER1 | |
| SCHEMBL4795246 | 0.81 | PTGER1 (0.71) | PTGER1 | |
| SCHEMBL3180838 | 0.77 | PTGER1 (0.61) | PTGER1 | |
| Hydrochloric Acid SCHEMBL3187915 | 0.76 | PTGER1 (0.61) | PTGER1 | |
| SCHEMBL3847522 | 0.75 | PTGER1 (0.45) | PTGER1 | |
| SCHEMBL3186192 | 0.74 | PTGER1 (0.48) | PTGER1 | |
| SCHEMBL3844837 | 0.73 | PTGER1 (0.61) | PTGER1 | |
| SCHEMBL3176032 | 0.72 | PTGER1 (0.67) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2106398-A2 | ISOQUINOLINECARBOXAMIDES AS INHIBITORS OF STEAROYL-COA DESATURASE (SCD) | SmithKline Beecham Corporation (US) | 2009-10-07 | — | — | EP | disclosed |
| WO-2008074832-A2 | ISOQUINOLINECARBOXAMIDES AS INHIBITORS OF STEAROYL-COA DESATURASE ( SCD) | SMITHKLINE BEECHAM CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |