SCHEMBL3854872

SCHEMBL3854872

C=C(C)C(=O)Oc1ccc(O)cc1-c1cccc2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.40
ADK P55263 1/20 0.40
SLC6A9 P48067 1/20 0.40
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
ALOX5 P09917 1/20 0.38
ALDH1A1 P00352 1/20 0.38
PGR P06401 1/20 0.38
GAA P10253 1/20 0.38
PTGS1 P23219 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
BACE1 P56817 1/20 0.38
MCL1 Q07820 1/20 0.37
ACMSD Q8TDX5 1/20 0.37
DHODH Q02127 1/20 0.37
C5AR1 P21730 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28421323 0.86 ALDH1A1 (0.46) GSK3BADKMAPTCYP2C9CYP2C19
SCHEMBL9794488 0.83 MCL1 (0.43) SLC6A9MAPTCYP2C9CYP2C19ESR1
SCHEMBL1939486 0.80 GSK3B (0.49) GSK3BADKMAPTALDH1A1PGR
SCHEMBL10040366 0.79 MTNR1A (0.45) MAPTALDH1A1PGRGAAPTGS1
SCHEMBL29373404 0.77 ALDH1A1 (0.60) ALOX5ALDH1A1PGRGAAPTGS1
SCHEMBL67480 0.77 ALDH1A1 (0.60) ALOX5ALDH1A1PGRGAAPTGS1
SCHEMBL10040386 0.76 ALDH1A1 (0.42) ESR1ALDH1A1PGRGAAPTGS1
SCHEMBL32667385 0.76 ALDH1A1 (0.42) ESR1ALDH1A1PGRGAAPTGS1
SCHEMBL10040371 0.75 NQO2 (0.44) MAPTCYP2C19ALDH1A1PGRGAA
SCHEMBL12416577 0.74 MAPT (0.53) MAPTALDH1A1PGRGAAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2009029801-A NAPHTHOHYDROQUINONE MONO(METH)ACRYLATE AND METHOD FOR PRODUCING THE SAME MITSUBISHI CHEMICALS CORP 2009-02-12 JP disclosed