SCHEMBL385501

SCHEMBL385501

OB(O)c1ccc(Cl)cc1F

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.41
ALDH1A1 P00352 2/20 0.37
KMT2A Q03164 1/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
LMNA P02545 1/20 0.36
KCNH2 Q12809 1/20 0.36
SLC6A3 Q01959 1/20 0.36
TSHR P16473 2/20 0.34
HSD17B10 Q99714 2/20 0.34
CYP3A4 P08684 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CCR2 P41597 1/20 0.34
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
NPC1 O15118 1/20 0.34
KMO O15229 1/20 0.33
ERN1 O75460 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29643703 1.00 ENPP2 (0.41) ENPP2ALDH1A1KMT2ASLC6A2SLC6A4
SCHEMBL2404902 0.86 KMT2A (0.36) ENPP2ALDH1A1KMT2ALMNATSHR
SCHEMBL246398 0.84 ENPP2 (0.42) ENPP2ALDH1A1KMT2ALMNATSHR
SCHEMBL31208432 0.84 ENPP2 (0.42) ENPP2ALDH1A1KMT2ALMNATSHR
SCHEMBL39406 0.76 CES2 (0.43) ALDH1A1KMT2ATDP1
SCHEMBL29375771 0.76 TSHR (0.48) ENPP2ALDH1A1KMT2ASLC6A2LMNA
SCHEMBL12384874 0.76 ESR2 (0.36) LMNAHSD17B10ERN1
SCHEMBL29395656 0.76 CES2 (0.43) ALDH1A1KMT2ATDP1
SCHEMBL41990 0.76 TSHR (0.48) ENPP2ALDH1A1KMT2ASLC6A2LMNA
SCHEMBL31414880 0.76 ERN1 (0.36) ENPP2ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
WO-2024016826-A1 6-POSITION SUBSTITUTED DIHYDROBENZO[E][1,2,3]OXATHIAZINE 2,2-DIOXIDE COMPOUND, PREPARATION THEREFOR, AND USE THEREOF 杭州市第七人民医院 2024-01-25 WO claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-20230363426-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-16 US claimed
US-11793220-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2023-10-24 US claimed
CN-116916755-A Materials and methods for extending the shelf life of food products JP实验室公司 2023-10-20 CN claimed
CN-115232090-A 6-substituted dihydrobenzo [ e ] [1,2,3] oxathiazine 2,2-dioxide compound and preparation and application thereof 杭州市第七人民医院 2022-10-25 CN claimed
US-20220264914-A1 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. 2022-08-25 US claimed
EP-2736912-B1 METHODS OF ISOLATING 4-CHLORO-2-FLUORO-3-SUBSTITUTED-PHENYLBORONIC ACIDS DOW AGROSCIENCES LLC (US) 2018-06-13 EP claimed
EP-2797933-B1 METHODS OF FORMING 4-CHLORO-2-FLUORO-3-SUBSTITUTED-PHENYLBORONIC ACID PINACOL ESTERS AND METHODS OF USING THE SAME DOW AGROSCIENCES LLC (US) 2017-08-16 EP claimed
US-20120065404-A1 Process for Preparing Ethyl (s)-2-Ethoxy-4-[N-[1-(2-Piperidinophenyl)-3-Methyl-1-Butyl]Aminocarbonyl Methyl]Benzoate and Use Thereof for the Preparation of Repaglinide ACTAVIS GROUP PTC HF (IS) 2012-03-15 US claimed
US-8101769-B2 Chemical intermediate; high purity drug ACTAVIS GROUP PTC EHF (IE) 2012-01-24 US claimed
US-20100197732-A1 Repaglinide Substantially Free of Dimer Impurity ACTAVIS GROUP PTC EHF (IS) 2010-08-05 US claimed
EP-2155706-A2 REPAGLINIDE SUBSTANTIALLY FREE OF DIMER IMPURITY Actavis Group PTC EHF (IS) 2010-02-24 EP claimed
EP-2121644-A2 IMPROVED PROCESS FOR PREPARING ETHYL (S)-2-ETHOXY-4-[N-[1-(2- PIPERIDINOPHENYL)-3-METHYL-1-BUTYL]AMINOCARBONYL METHYL]BENZOATE AND USE THEREOF FOR THE PREPARATION OF REPAGLINIDE Actavis Group PTC EHF (IS) 2009-11-25 EP claimed
WO-2009004485-A2 REPAGLINIDE SUBSTANTIALLY FREE OF DIMER IMPURITY ACTAVIS GROUP PTC EHF (IS) 2009-01-08 WO claimed
US-20080200684-A1 Process for Preparing Ethyl (s)-2-Ethoxy-4-[N-[1-(2-Piperidinophenyl)-3-Methyl-1-Butyl]Aminocarbonyl Methyl]Benzoate and Use Thereof for the Preparation of Repaglinide ACTAVIS GROUP PTC HF (IS) 2008-08-21 US claimed
WO-2008099286-A2 IMPROVED PROCESS FOR PREPARING ETHYL (S)-2-ETHOXY-4-[N-[1-(2- PIPERIDINOPHENYL)-3-METHYL-1-BUTYL]AMINOCARBONYL METHYL]BENZOATE AND USE THEREOF FOR THE PREPARATION OF REPAGLINIDE ACTAVIS GROUP PTC EHF (US) 2008-08-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100197732-A1 Repaglinide Substantially Free of Dimer Impurity EMG1, DAP3, DRD4 ENPP2 3348/4885ALDH1A1 1800/4885KMT2A 2316/4885
US-20120065404-A1 Process for Preparing Ethyl (s)-2-Ethoxy-4-[N-[1-(2-Piperidinophenyl)-3-Methyl-1-Butyl]Aminocarbonyl Methyl]Benzoate and Use Thereof for the Preparation of Repaglinide MEP1B, GABRE, BPGM ENPP2 2365/4885ALDH1A1 1646/4885KMT2A 958/4885
US-20080200684-A1 Process for Preparing Ethyl (s)-2-Ethoxy-4-[N-[1-(2-Piperidinophenyl)-3-Methyl-1-Butyl]Aminocarbonyl Methyl]Benzoate and Use Thereof for the Preparation of Repaglinide MEP1B, GABRE, BPGM ENPP2 2365/4885ALDH1A1 1646/4885KMT2A 958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.