Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294810 | 0.97 | TSHR (0.74) | TSHRLMNATRPA1ALDH1A1TDP1 | |
| SCHEMBL17967785 | 0.97 | TSHR (0.74) | TSHRLMNATRPA1ALDH1A1TDP1 | |
| SCHEMBL5799889 | 0.95 | TSHR (0.70) | TSHRLMNATRPA1ALDH1A1TDP1 | |
| SCHEMBL4210996 | 0.95 | TSHR (0.70) | TSHRLMNATRPA1ALDH1A1TDP1 | |
| SCHEMBL11342987 | 0.90 | TSHR (0.79) | TSHRLMNATRPA1ALDH1A1TDP1 | |
| Alcohol SCHEMBL3854623 | 0.86 | TSHR (0.94) | TSHRLMNATRPA1ALDH1A1TDP1 | |
| SCHEMBL22659 | 0.83 | — | — | |
| SCHEMBL7753346 | 0.83 | TSHR (1.00) | TSHRLMNATRPA1ALDH1A1TDP1 | |
| SCHEMBL1204819 | 0.83 | — | — | |
| SCHEMBL1203795 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697287-B1 | IMPROVEMENTS IN OR RELATING TO HYDROGENATION | EXXONMOBIL CHEM PATENTS INC (US) | 2015-08-26 | — | — | EP | disclosed |
| EP-0804402-B1 | ORGANIC COMPOUNDS AND PROCESSES FOR THEIR MANUFACTURE | EXXONMOBIL CHEM PATENTS INC (US) | 2009-10-07 | — | — | EP | disclosed |
| US-7586017-B2 | Hydrogenation | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-09-08 | — | — | US | disclosed |
| US-20070161829-A1 | Improvements in or relating to hydrogenation | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-07-12 | — | — | US | disclosed |
| EP-1697287-A1 | IMPROVEMENTS IN OR RELATING TO HYDROGENATION | ExxonMobil Chemical Patents Inc. (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058782-A1 | IMPROVEMENTS IN OR RELATING TO HYDROGENATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-06-30 | — | — | WO | disclosed |
| US-6307093-B1 | ESTERS OF BRANCHED C.SUB.9 ALCOHOLS SUITABLE AS PLASTICIZERS; C6 ALDEHYDE AND A SATURATED ALIPHATIC C9 ALDEHYDE; REFRIGERANT LUBRICANTS | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-10-23 | — | — | US | disclosed |
| US-6090986-A | MANUFACTURE OF A SATURATED ALIPHATIC ALDEHYDE CONTAINING A TOTAL OF 9 CARBON ATOMS WHICH COMPRISES SUBJECTING A SATURATED C6 ALDEHYDE TO AN ALDOL CONDENSATION WITH PROPANAL TO FORM AN UNSATURATED C9 ALDEHYDE, AND HYDROGENATION | EXXON CHEMICAL PATENTS INC. (US) | 2000-07-18 | — | — | US | disclosed |
| WO-1998002406-A1 | RECYCLE AND RECOVERY OF USEFUL PRODUCTS FROM HEAVY ALDOL BY-PRODUCTS | EXXON CHEMICAL PATENTS, INC. (US) | 1998-01-22 | — | — | WO | disclosed |
| EP-0804402-A1 | ORGANIC COMPOUNDS AND PROCESSES FOR THEIR MANUFACTURE | EXXON CHEMICAL PATENTS INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022268-A1 | ORGANIC COMPOUNDS AND PROCESSES FOR THEIR MANUFACTURE | EXXON CHEMICAL PATENTS INC. (US) | 1996-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161829-A1 | Improvements in or relating to hydrogenation | ADH5, ADH1C, ADH1A | TSHR 1518/4885LMNA 4769/4885TRPA1 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.