SCHEMBL3855828

SCHEMBL3855828

Cc1sc(-c2ccccc2)cc1C1=C(c2c(C)sc(-c3ccccc3)c2C)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PLA2G10 O15496 1/20 0.34
PTP4A3 O75365 2/20 0.34
PTP4A2 Q12974 1/20 0.33
PTP4A1 Q93096 1/20 0.33
HSD17B1 P14061 1/20 0.32
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3851690 0.90 ESR1 (0.30)
SCHEMBL423920 0.87 PLA2G10 (0.41) PLA2G10PTP4A3PTP4A2PTP4A1HSD17B1
SCHEMBL1043494 0.87 GRM6 (0.36) NPC1ALDH1A1LMNAHPGDRAB9A
SCHEMBL3858306 0.86 APP (0.35) NPC1ALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL6236956 0.83 ALOX5 (0.36) NPC1ALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL20702041 0.80 GRM6 (0.34) ALDH1A1HPGDSMN1; SMN2
SCHEMBL23169718 0.80 PLA2G10 (0.37) PLA2G10PTP4A3PTP4A2PTP4A1HSD17B1
SCHEMBL13164291 0.80 ESR1 (0.42) PLA2G10HSD17B1LMNA
SCHEMBL3008443 0.79 PLA2G10 (0.38) PLA2G10PTP4A3PTP4A2PTP4A1HSD17B1
SCHEMBL15255340 0.78 PLA2G10 (0.38) PLA2G10PTP4A3PTP4A2PTP4A1HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3732533-B1 SYSTEM AND METHOD FOR CUSTOMIZATION OF A PHOTOCHROMIC ARTICLE TRANSITIONS OPTICAL LTD (IE) 2025-12-10 EP disclosed
US-11609442-B2 System and method for customization of a photochromic article TRANSITIONS OPTICAL, LTD. (IE) 2023-03-21 US disclosed
US-20210055575-A1 System and Method for Customization of a Photochromic Article TRANSITIONS OPTICAL, LTD. (IE) 2021-02-25 US disclosed
CN-111527442-A System and method for customizing photochromic articles 光学转变有限公司 2020-08-11 CN disclosed
US-8444450-B2 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. (JP) 2013-05-21 US disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 US disclosed
EP-1637570-B1 Color-memorizing photochromic writing instrument PILOT INK CO LTD (JP) 2007-06-27 EP disclosed
CN-1315555-C Method of alternatively dioplaying photochromic action of memory color in toy assembly, and photochromic toy having alternatively color memory PILOT INK CO LTD (JP) 2007-05-16 CN disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 US disclosed
EP-1637570-A1 Color-memorizing photochromic writing instrument THE PILOT INK CO., LTD. (JP) 2006-03-22 EP disclosed
US-20060053975-A1 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. 2006-03-16 US disclosed
EP-1415692-B1 Method of changing color of a toy and colour changing toy PILOT INK CO LTD (JP) 2005-05-04 EP disclosed
US-20040135097-A1 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. 2004-07-15 US disclosed
CN-1498666-A Method of alternatively dioplaying photochromic action of memory color in toy assembly, and photochromic toy having alternatively color memory ��ī�����˹��ʽ���� 2004-05-26 CN disclosed
EP-1415692-A1 Method of changing color of a toy and colour changing toy THE PILOT INK CO., LTD. (JP) 2004-05-06 EP disclosed