Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.76 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3857090 | 0.83 | PTGS1 (0.56) | ALOX5PTGS1PTGS2PTGDR2 | |
| SCHEMBL14595449 | 0.82 | ALOX5 (0.58) | ALOX5PTGS1PTGS2HSD17B10HTR2A | |
| SCHEMBL15101429 | 0.76 | ALOX5 (0.67) | ALOX5PTGS1PTGS2HSD17B10HTR2A | |
| SCHEMBL3853703 | 0.76 | ALOX5 (0.48) | ALOX5PTGS1PTGS2 | |
| SCHEMBL3861613 | 0.75 | ALOX5 (0.65) | ALOX5PTGS1PTGS2BAZ2BHSD17B10 | |
| SCHEMBL13877233 | 0.75 | ALOX5 (0.65) | ALOX5PTGS1PTGS2HTR2AHTR2C | |
| SCHEMBL1873708 | 0.75 | PTGS1 (0.65) | ALOX5PTGS1PTGS2BAZ2BHSD17B10 | |
| SCHEMBL3853296 | 0.75 | CA1 (0.59) | PTGS1PTGS2PTGDR2 | |
| SCHEMBL17895804 | 0.75 | PTGS1 (0.68) | ALOX5PTGS1PTGS2PTGDR2BAZ2B | |
| SCHEMBL13478780 | 0.74 | PTGS1 (0.64) | ALOX5PTGS1PTGS2BAZ2BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | ALOX5 1638/4885PTGS1 2152/4885PTGS2 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.