Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | HTR5A | P47898 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616130 | 0.88 | ALOX5 (0.61) | PTGS1PTGS2ALOX5HTR6DRD2 | |
| SCHEMBL3857095 | 0.83 | ALOX5 (0.76) | PTGS1PTGS2ALOX5PTGDR2 | |
| SCHEMBL3853703 | 0.81 | ALOX5 (0.48) | PTGS1PTGS2ALOX5HTR6HTR5A | |
| SCHEMBL14595449 | 0.80 | ALOX5 (0.58) | PTGS1PTGS2ALOX5 | |
| SCHEMBL17722992 | 0.78 | L3MBTL1 (0.61) | ATM | |
| SCHEMBL3859121 | 0.78 | HTR6 (0.67) | PTGS1PTGS2HTR6PTGDR2 | |
| SCHEMBL12983538 | 0.78 | MCHR1 (0.75) | MCHR1 | |
| SCHEMBL3859716 | 0.75 | ALOX5 (0.45) | PTGS1PTGS2ALOX5HTR6DRD2 | |
| SCHEMBL15101429 | 0.74 | ALOX5 (0.67) | PTGS1PTGS2ALOX5HTR6 | |
| SCHEMBL13877233 | 0.73 | ALOX5 (0.65) | PTGS1PTGS2ALOX5HTR6HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | PTGS1 2152/4885PTGS2 1495/4885ALOX5 1638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.