Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.30 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.30 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.30 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL4954723 | 0.84 | LTA4H (0.35) | DPP7SLC7A5LTA4HL3MBTL1CHRM1 | |
| SCHEMBL385711 | 0.84 | L3MBTL1 (0.36) | DPP7LTA4HL3MBTL1CHRM1MME | |
| SCHEMBL385712 | 0.84 | L3MBTL1 (0.36) | DPP7LTA4HL3MBTL1CHRM1MME | |
| SCHEMBL383047 | 0.82 | L3MBTL1 (0.39) | DPP7LTA4HL3MBTL1CHRM1MME | |
| SCHEMBL383046 | 0.82 | L3MBTL1 (0.39) | DPP7LTA4HL3MBTL1CHRM1MME | |
| Glycine SCHEMBL4955873 | 0.81 | GLRA1 (0.36) | DPP7LTA4HL3MBTL1CHRM1MME | |
| Threonine SCHEMBL4955781 | 0.79 | SLC7A5 (0.36) | DPP7SLC7A5LTA4H | |
| SCHEMBL4956023 | 0.78 | DPP7 (0.38) | DPP7SLC7A5SLC1A1LTA4HSLC1A3 | |
| Pyrrole SCHEMBL28327955 | 0.74 | L3MBTL1 (0.38) | L3MBTL1 | |
| Serine SCHEMBL28242846 | 0.72 | SLC1A1 (0.52) | DPP7SLC7A5SLC1A1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439226-B2 | Serine protease inhibitors | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-10-21 | — | — | US | disclosed |
| WO-2006043933-A1 | SERINE PROTEASE INHIBITORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20050130883-A1 | Serine protease inhibitors | THE GOV. OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICES | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130883-A1 | Serine protease inhibitors | PRSS1, TASP1, METAP1 | DPP7 173/4885SLC7A5 2539/4885SLC1A1 2625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.