Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 6/20 | 0.59 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5088352 | 1.00 | BDKRB2 (0.59) | BDKRB2CSNK1EDNM1KCNH2MEN1 | |
| Iodide SCHEMBL5088210 | 1.00 | BDKRB2 (0.59) | BDKRB2CSNK1EDNM1KCNH2MEN1 | |
| Iodide SCHEMBL5087228 | 1.00 | BDKRB2 (0.59) | BDKRB2CSNK1EDNM1KCNH2MEN1 | |
| Iodide SCHEMBL5088222 | 1.00 | BDKRB2 (0.59) | BDKRB2CSNK1EDNM1KCNH2MEN1 | |
| Iodide SCHEMBL5092116 | 1.00 | BDKRB2 (0.59) | BDKRB2CSNK1EDNM1KCNH2MEN1 | |
| Iodide SCHEMBL3861081 | 1.00 | BDKRB2 (0.59) | BDKRB2CSNK1EDNM1KCNH2MEN1 | |
| Iodide SCHEMBL5087915 | 1.00 | BDKRB2 (0.59) | BDKRB2CSNK1EDNM1KCNH2MEN1 | |
| Iodide SCHEMBL5091551 | 1.00 | BDKRB2 (0.59) | BDKRB2CSNK1EDNM1KCNH2MEN1 | |
| Iodide SCHEMBL5087211 | 0.98 | BDKRB2 (0.61) | BDKRB2CSNK1EDNM1KCNH2MEN1 | |
| Iodide SCHEMBL5091515 | 0.96 | BDKRB2 (0.59) | BDKRB2CSNK1EDNM1KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238606-B1 | Methyl-Iodide-free carbonylation of methanol to acetaldehyde | EASTMAN CHEMICAL COMPANY (US) | 2016-01-19 | — | — | US | claimed |
| US-9718754-B2 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2017-08-01 | — | — | US | disclosed |
| US-9714206-B2 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-20160251292-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-09-01 | — | — | US | disclosed |
| US-20160185701-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-06-30 | — | — | US | disclosed |
| US-20160185700-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-06-30 | — | — | US | disclosed |
| US-9365479-B1 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2016-06-14 | — | — | US | disclosed |
| US-9266807-B1 | Conversion of alcohols to longer chain aldehydes or alcohols | EASTMAN CHEMICAL COMPANY (US) | 2016-02-23 | — | — | US | disclosed |
| US-9238606-B1 | Methyl-Iodide-free carbonylation of methanol to acetaldehyde | EASTMAN CHEMICAL COMPANY (US) | 2016-01-19 | — | — | US | disclosed |
| EP-1501779-B1 | CONTINUOUS CARBONYLATION PROCESS | EASTMAN CHEM CO (US) | 2009-12-23 | — | — | EP | disclosed |
| US-6201138-B1 | CONTACTING A GAMMA, DELTA-EPOXYALKENE OR A GAMMA, DELTA-EPOXYCYCLOALKENE IN LIQUID PHASE WITH SOLUTION OF CATALYTIC AMOUNT OF ORGANOTIN (IV) OR ORGANOANTIMONY COMPOUND IN INERT ORGANIC SOLVENT AND QUATERNARY ORGANIC ONIUM IODIDE | EASTMAN CHEMICAL COMPANY | 2001-03-13 | — | — | US | disclosed |
| EP-0624157-B1 | CONTINUOUS PROCESS FOR THE MANUFACTURE OF 2,5-DIHYDROFURANS FROM GAMMA,DELTA-EPOXYBUTENES | EASTMAN CHEM CO (US) | 1997-03-05 | — | — | EP | disclosed |
| US-5591874-A | ISOMERIZATION OF VINYL ETHYLENE CARBONATE COMPOUND USING CATALYST SYSTEM COMPRISING ACIDIC AND HALOGEN COMPONENTS | EASTMAN CHEMICAL COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0518973-B1 | ISOMERIZATION OF EPOXYALKENES TO 2,5-DIHYDROFURANS AND CATALYSTS COMPOSITIONS USEFUL THEREFOR | EASTMAN CHEM CO (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0624157-A1 | CONTINUOUS PROCESS FOR THE MANUFACTURE OF 2,5-DIHYDROFURANS FROM -g(g),-g(d)-EPOXYBUTENES. | EASTMAN CHEM CO (US) | 1994-11-17 | — | — | EP | disclosed |
| US-5315019-A | Continuous process for the manufacture of 2,5-dihydrofurans from γ, δ-epoxybutenes | EASTMAN CHEMICAL COMPANY (US) | 1994-05-24 | — | — | US | disclosed |
| WO-1993010111-A1 | CONTINUOUS PROCESS FOR THE MANUFACTURE OF 2,5-DIHYDROFURANS FROM η,δ-EPOXYBUTENES | EASTMAN KODAK COMPANY (US) | 1993-05-27 | — | — | WO | disclosed |
| EP-0518973-A1 | ISOMERIZATION OF EPOXYALKENES TO 2,5-DIHYDROFURANS AND CATALYSTS COMPOSITIONS USEFUL THEREFOR. | EASTMAN KODAK CO (US) | 1992-12-23 | — | — | EP | disclosed |
| US-5082956-A | Quaternary onium iodide catalyst | EASTMAN KODAK COMPANY (US) | 1992-01-21 | — | — | US | disclosed |
| WO-1991013882-A1 | ISOMERIZATION OF EPOXYALKENES TO 2,5-DIHYDROFURANS AND CATALYSTS COMPOSITIONS USEFUL THEREFOR | EASTMAN KODAK COMPANY (US) | 1991-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185701-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | ADH1C, ADH5, ADH1A | BDKRB2 4374/4885CSNK1E 1502/4885DNM1 3478/4885 |
| US-20160251292-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | ADH1C, ADH5, ADH1A | BDKRB2 4280/4885CSNK1E 1480/4885DNM1 3463/4885 |
| US-20160185700-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | ADH1C, ADH5, ADH1A | BDKRB2 4280/4885CSNK1E 1480/4885DNM1 3463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.