SCHEMBL385769

SCHEMBL385769

CCC(C)COc1cc[c]cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.46
MAOA P21397 1/20 0.39
PTGS1 P23219 1/20 0.39
GPR88 Q9GZN0 7/20 0.39
GPBAR1 Q8TDU6 1/20 0.38
LMNA P02545 1/20 0.38
TLR8 Q9NR97 1/20 0.36
MCHR1 Q99705 1/20 0.36
CDK1 P06493 1/20 0.36
CCNB1 P14635 1/20 0.36
CCNA2 P20248 1/20 0.36
CDK2 P24941 1/20 0.36
CCNA1 P78396 1/20 0.36
MAPT P10636 1/20 0.35
NQO1 P15559 1/20 0.34
SIGMAR1 Q99720 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8072049 1.00 FFAR1 (0.46) FFAR1MAOAPTGS1GPR88GPBAR1
SCHEMBL4776330 1.00 FFAR1 (0.46) FFAR1MAOAPTGS1GPR88GPBAR1
SCHEMBL6538984 0.85 GPR88 (0.41) GPR88
SCHEMBL5259492 0.82 MAOA (0.38) FFAR1MAOAPTGS1LMNASIGMAR1
SCHEMBL7369438 0.82 MAOA (0.38) FFAR1MAOAPTGS1LMNAMAPT
SCHEMBL3090326 0.82 MAOA (0.36) FFAR1MAOAPTGS1GPR88LMNA
SCHEMBL159889 0.81 MAPT (0.43) MAOAPTGS1LMNAMAPT
SCHEMBL1462725 0.81 TDP1 (0.42) FFAR1NQO1SIGMAR1
SCHEMBL15653500 0.80 CYP2C9 (0.41) FFAR1MAOAPTGS1GPR88LMNA
SCHEMBL10406354 0.79 TDP1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9150670-B2 Near-infrared absorptive dye-containing curable composition, ink composition and method of producing near-infrared absorptive filter FUJIFILM CORPORATION (JP) 2015-10-06 US claimed
EP-0766665-B1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARM (GB) 1999-07-28 EP claimed
EP-3009479-B1 CURABLE COMPOSITION, CURED FILM, NEAR INFRARED CUT FILTER, CAMERA MODULE AND METHOD FOR MANUFACTURING CAMERA MODULE FUJIFILM CORP (JP) 2021-12-15 EP disclosed
US-10901123-B2 Curable composition, cured film, near infrared cut filter, camera module and method for manufacturing camera module FUJIFILM CORPORATION (JP) 2021-01-26 US disclosed
US-10208212-B2 Near-infrared absorption composition, curable composition, cured film, near-infrared cut filter, solid-state imaging device, infrared sensor, camera module, processed coloring agent, and method of manufacturing processed coloring agent FUJIFILM CORPORATION (JP) 2019-02-19 US disclosed
US-9958576-B2 Near infrared ray absorbent composition, near infrared ray cut filter, manufacturing method of near infrared ray cut filter, solid image pickup element, camera module FUJIFILM CORPORATION (JP) 2018-05-01 US disclosed
US-9897731-B2 Infrared ray cutting film, infrared ray cutting laminated glass, and infrared ray cutting member FUJIFILM CORPORATION (JP) 2018-02-20 US disclosed
US-9740095-B2 Green coloring composition for use in color filter, colored film, color filter, and solid-state imaging device FUJIFILM CORPORATION (JP) 2017-08-22 US disclosed
EP-3202855-A1 NEAR-INFRARED ABSORBING COMPOSITION, CURABLE COMPOSITION, CURED FILM, NEAR-INFRARED BLOCKING FILTER, SOLID-STATE IMAGING ELEMENT, INFRARED SENSOR, CAMERA MODULE, PROCESSED DYE AND METHOD FOR PRODUCING PROCESSED DYE FUJIFILM Corporation (JP) 2017-08-09 EP disclosed
US-20170190923-A1 NEAR-INFRARED ABSORPTION COMPOSITION, CURABLE COMPOSITION, CURED FILM, NEAR-INFRARED CUT FILTER, SOLID-STATE IMAGING DEVICE, INFRARED SENSOR, CAMERA MODULE, PROCESSED COLORING AGENT, AND METHOD OF MANUFACTURING PROCESSED COLORING AGENT FUJIFILM CORPORATION (JP) 2017-07-06 US disclosed
US-20170174869-A1 COMPOSITION, METHOD OF MANUFACTURING COMPOSITION, CURABLE COMPOSITION, CURED FILM, NEAR-INFRARED CUT FILTER, SOLID-STATE IMAGING DEVICE, INFRARED SENSOR, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-06-22 US disclosed
CN-1610712-A Process for preparing aryl-aryl coupling compounds COVION ORGANIC SEMICONDUCTORS (DE) 2005-04-27 CN disclosed
US-20050043386-A1 Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these SANKYO COMPANY, LIMITED (JP) 2005-02-24 US disclosed
EP-1471054-A1 AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE Sankyo Company, Limited (JP) 2004-10-27 EP disclosed
US-20040132784-A1 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2004-07-08 US disclosed
CN-1494540-A Amino alcohol derivatives ������������ʽ���� 2004-05-05 CN disclosed
US-6723745-B2 PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL SANKYO COMPANY, LIMITED (JP) 2004-04-20 US disclosed
US-20030236297-A1 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2003-12-25 US disclosed
EP-1300405-A1 AMINO ALCOHOL DERIVATIVES Sankyo Company, Limited (JP) 2003-04-09 EP disclosed
US-5277838-A Silylated benzoic acid derivatives CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1994-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030236297-A1 Amino alcohol derivatives CD4, ADH1C, ADH1A FFAR1 246/4885MAOA 2367/4885PTGS1 408/4885
US-20050043386-A1 Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these PHOSPHO1, CD4, FCGRT FFAR1 78/4885MAOA 3259/4885PTGS1 660/4885
US-20040132784-A1 Amino alcohol derivatives CD4, ADH1C, ADH1A FFAR1 246/4885MAOA 2367/4885PTGS1 408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.