Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961842 | 0.84 | PTGS1 (0.59) | PTGS2AKR1B1PTGER1PTGER4PTGER3 | |
| SCHEMBL538512 | 0.84 | KMT2A (0.60) | PTGS2AKR1B1PTGER1PTGER4PTGER3 | |
| SCHEMBL1997164 | 0.82 | DRD1 (0.51) | DRD1DRD2DRD4DRD5DRD3 | |
| Ammonia Solution, Strong SCHEMBL27926479 | 0.82 | KMT2A (0.58) | PTGS2AKR1B1PTGER1PTGER4PTGER3 | |
| SCHEMBL28594606 | 0.82 | KMT2A (0.58) | PTGS2AKR1B1PTGER1PTGER4PTGER3 | |
| SCHEMBL27701716 | 0.82 | KMT2A (0.58) | PTGS2AKR1B1PTGER1PTGER4PTGER3 | |
| Hydrochloric Acid SCHEMBL11895689 | 0.82 | KMT2A (0.58) | PTGS2AKR1B1PTGER1PTGER4PTGER3 | |
| SCHEMBL29512995 | 0.82 | KMT2A (0.58) | PTGS2AKR1B1PTGER1PTGER4PTGER3 | |
| SCHEMBL8645744 | 0.82 | PTGS1 (0.55) | PTGS2AKR1B1PTGER1PTGER4PTGER3 | |
| SCHEMBL1919862 | 0.81 | DRD1 (0.46) | DRD1DRD2DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250325542-A1 | INHIBITORS OF ANTIMOCROBIAL RESISTANCE AND METHOS USING SAME | BAYLOR COLLEGE MEDICINE (US) | 2025-10-23 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-7576215-B2 | Quinolines and pharmaceutical compositions thereof | WYETH (US) | 2009-08-18 | — | — | US | disclosed |
| EP-1692111-A2 | QUINOLINES USEFUL IN TREATING CARDIOVASCULAR DISEASE | Wyeth, A Corporation of the State of Delaware (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005058834-A2 | QUINOLINES USEFUL IN TREATING CARDIOVASCULAR DISEASE | WYETH (US) | 2005-06-30 | — | — | WO | disclosed |
| US-20050131014-A1 | Quinolines useful in treating cardiovascular disease | WYETH (US) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325542-A1 | INHIBITORS OF ANTIMOCROBIAL RESISTANCE AND METHOS USING SAME | BPGM, PNMT, DDT | PTGS2 1125/4885AKR1B1 3455/4885DRD1 1771/4885 |
| US-20050131014-A1 | Quinolines useful in treating cardiovascular disease | NR1H2, NR1H3, SREBF1 | PTGS2 958/4885AKR1B1 344/4885DRD1 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.