SCHEMBL3859664

SCHEMBL3859664

Cc1cc(-c2ccc(OS(C)(=O)=O)c(C)c2)ccc1OS(C)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
CYP1A2 P05177 1/20 0.44
ALPL P05186 1/20 0.44
HSD17B10 Q99714 1/20 0.44
STS P08842 3/20 0.44
PTGS2 P35354 5/20 0.43
CA2 P00918 4/20 0.41
CA1 P00915 2/20 0.41
CA9 Q16790 2/20 0.41
KDM4E B2RXH2 2/20 0.41
KMT2A Q03164 1/20 0.41
CA12 O43570 2/20 0.39
PTGS1 P23219 2/20 0.39
PDE4B Q07343 1/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CDK4 P11802 1/20 0.36
CCND1 P24385 1/20 0.36
PDGFRB P09619 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937925 0.83 CA1 (0.55) TSHRCYP1A2ALPLHSD17B10STS
SCHEMBL11576553 0.80 CYP1A2 (0.42) TSHRCYP1A2ALPLHSD17B10STS
SCHEMBL9024638 0.80 PTGS2 (0.42) TSHRCYP1A2ALPLHSD17B10STS
SCHEMBL13342828 0.80 TSHR (0.47) TSHRCYP1A2ALPLHSD17B10PTGS2
SCHEMBL3845198 0.79 CA2 (0.42) TSHRCYP1A2ALPLHSD17B10STS
SCHEMBL9958325 0.79 CA1 (0.45) TSHRCYP1A2ALPLHSD17B10CA2
SCHEMBL3840251 0.79 CA1 (0.46) TSHRCYP1A2ALPLHSD17B10STS
SCHEMBL3843216 0.78 PTGS2 (0.47) PTGS2CA2CA12PTGS1
SCHEMBL7210487 0.76 MRGPRX4 (0.43) TSHRCYP1A2ALPLHSD17B10STS
SCHEMBL6941469 0.76 TSHR (0.40) TSHRCYP1A2ALPLHSD17B10STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2112133-B1 Halogenated aromatic compound, polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2012-07-04 EP disclosed
EP-2112133-A1 Halogenated aromatic compound, polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2009-10-28 EP disclosed
EP-1245555-B1 Halogenated aromatic compound, polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2009-08-19 EP disclosed
US-7556860-B2 Laminate and method of forming the same, insulating film, and semiconductor device JSR CORPORATION (JP) 2009-07-07 US disclosed
EP-1482589-B1 Manufacturing process of membrane-electrode assemblies JSR CORP (JP) 2009-02-18 EP disclosed
EP-1245638-B1 Composition for insulating film formation JSR CORP (JP) 2009-01-14 EP disclosed
US-7396607-B2 Manufacturing process for membrane-electrode assemblies JSR CORPORATION (JP) 2008-07-08 US disclosed
EP-1188807-B1 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR CORP (JP) 2007-10-17 EP disclosed
EP-1298176-B1 Stacked film insulating film and substrate for semiconductor JSR CORP (JP) 2007-01-03 EP disclosed
US-7153767-B2 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR CORPORATION (JP) 2006-12-26 US disclosed
US-20020172652-A1 Composition for film formation and material for insulating film formation JSR CORPORATION (JP) 2002-11-21 US disclosed
EP-1245638-A1 Composition for insulating film formation JSR Corporation (JP) 2002-10-02 EP disclosed
EP-1245555-A1 Halogenated aromatic compound, polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed
EP-1245554-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed
US-20020064953-A1 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR CORPORATION (JP) 2002-05-30 US disclosed
EP-1188807-A2 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR Corporation (JP) 2002-03-20 EP disclosed
US-20010037000-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2001-11-01 US disclosed
EP-0956312-B1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR CORP (JP) 2001-10-10 EP disclosed
US-6300465-B1 Process for producing phenylene-containing polymer and film-forming material JSR CORPORATION (JP) 2001-10-09 US disclosed
EP-1138712-A2 Polyarylene copolymers and proton-conductive membrane JSR Corporation (JP) 2001-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020172652-A1 Composition for film formation and material for insulating film formation VCL, BMI1, PUF60 TSHR 4810/4885CYP1A2 412/4885ALPL 3061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.