Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11978140 | 0.82 | NQO1 (0.50) | HPGDTDP1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL9778602 | 0.79 | MAOB (0.47) | KCNH2HRH3HPGDTDP1ALDH1A1 | |
| SCHEMBL4609655 | 0.79 | KCNH2 (0.38) | KCNH2HRH3SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9779134 | 0.78 | KDM4E (0.45) | KCNH2HRH3HPGDSMN1; SMN2MAPT | |
| SCHEMBL9778840 | 0.78 | MAOB (0.49) | KCNH2HRH3HPGDTDP1ALDH1A1 | |
| SCHEMBL9778697 | 0.78 | KDM4E (0.44) | KCNH2HRH3SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9451018 | 0.78 | MEN1 (0.41) | SMN1; SMN2ALDH1A1MAPTTSHRLMNA | |
| SCHEMBL4741399 | 0.77 | KCNH2 (0.40) | KCNH2HRH3ALDH1A1MAPTLMNA | |
| SCHEMBL9778581 | 0.77 | LMNA (0.50) | HRH3SMN1; SMN2TP53MAPTLMNA | |
| SCHEMBL9778740 | 0.77 | DRD2 (0.43) | KCNH2HRH3HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828127-A4 | INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-äÝ4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL¨-(4-PIPERIDYL)üMETHANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-04-29 | — | — | EP | disclosed |
| EP-1828127-A2 | INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-äÝ4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL¨-(4-PIPERIDYL)üMETHANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006065659-A2 | INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-{[4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL]-(4-PIPERIDYL)}METHANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-06-22 | — | — | WO | disclosed |