Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3870016 | 0.99 | CFD (0.35) | CFDTPSB2NPC1RAB9AL3MBTL1 | |
| SCHEMBL3862437 | 0.83 | HAO1 (0.41) | CFDTPSB2NPC1RAB9AL3MBTL1 | |
| SCHEMBL3861228 | 0.81 | CFD (0.45) | CFDTPSB2 | |
| SCHEMBL3865749 | 0.76 | CFD (0.37) | CFDTPSB2RAB9A | |
| SCHEMBL3870084 | 0.75 | CFD (0.39) | CFDTPSB2 | |
| SCHEMBL1003362 | 0.72 | SIRT2 (0.45) | — | |
| SCHEMBL2151103 | 0.72 | SIRT2 (0.45) | — | |
| SCHEMBL3862235 | 0.72 | HAO1 (0.38) | CFDTPSB2HAO1 | |
| SCHEMBL3860383 | 0.72 | HAO1 (0.38) | CFDTPSB2HAO1 | |
| SCHEMBL2150738 | 0.72 | EPHX1 (0.38) | NPC1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076122-A2 | ALKYNYL PHENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | Acucela, Inc. (US) | 2009-07-08 | — | — | EP | disclosed |
| WO-2009005794-A2 | ALKYNYL PHENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2009-01-08 | — | — | WO | disclosed |