SCHEMBL3860282

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3852558	0.84	KMT2A (0.54)	KMT2AKLK7FTOCYP1A2CYP3A4
	SCHEMBL3853310	0.81	KMT2A (0.43)	KMT2AKLK7FTOCYP1A2CYP3A4
	SCHEMBL3852327	0.81	HPGD (0.54)	KMT2AKLK7ALDH1A1HPGDMAPT
	SCHEMBL3860317	0.79	ALDH1A1 (0.46)	KMT2ACYP1A2CYP3A4CYP2D6CYP2C19
	SCHEMBL4152854	0.78	KMT2A (0.48)	KMT2AKLK7CYP1A2CYP3A4CYP2D6
	SCHEMBL3850344	0.78	CYP2D6 (0.46)	KMT2AFTOCYP1A2CYP2D6ALDH1A1
	SCHEMBL14557208	0.77	KLK7 (0.57)	KMT2AKLK7FTOCYP1A2CYP3A4
	SCHEMBL3851575	0.75	KMT2A (0.67)	KMT2AKLK7FTOCYP1A2CYP3A4
	SCHEMBL7709776	0.75	KLK7 (0.53)	KMT2AKLK7ALDH1A1HPGDMAPT
	SCHEMBL3850799	0.73	FTO (0.56)	KMT2AFTOMAPTTHRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.