Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | CA1 | P00915 | 2/20 | 0.66 |
| ▸ | CA2 | P00918 | 2/20 | 0.66 |
| ▸ | BCHE | P06276 | 1/20 | 0.66 |
| ▸ | ACHE | P22303 | 1/20 | 0.66 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20526223 | 0.96 | ALDH1A1 (0.68) | ALDH1A1CYP3A4MAPK1HSD17B10TSHR | |
| Parathion SCHEMBL26857 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP3A4MAPK1HSD17B10TSHR | |
| Parathion SCHEMBL4751066 | 0.84 | ALDH1A1 (0.91) | ALDH1A1CYP3A4MAPK1HSD17B10TSHR | |
| Parathion SCHEMBL8779525 | 0.83 | ALDH1A1 (0.97) | ALDH1A1CYP3A4MAPK1HSD17B10TSHR | |
| Parathion SCHEMBL10436147 | 0.83 | ALDH1A1 (0.97) | ALDH1A1CYP3A4MAPK1HSD17B10TSHR | |
| Parathion SCHEMBL10447032 | 0.83 | ALDH1A1 (0.97) | ALDH1A1CYP3A4MAPK1HSD17B10TSHR | |
| SCHEMBL2545948 | 0.83 | CES2 (0.73) | ALDH1A1CYP3A4MAPK1HSD17B10TSHR | |
| Parathion SCHEMBL8960270 | 0.83 | ALDH1A1 (0.97) | ALDH1A1CYP3A4MAPK1HSD17B10TSHR | |
| Parathion SCHEMBL8960276 | 0.83 | ALDH1A1 (0.97) | ALDH1A1CYP3A4MAPK1HSD17B10TSHR | |
| Parathion SCHEMBL20271121 | 0.83 | ALDH1A1 (0.97) | ALDH1A1CYP3A4MAPK1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177989-A | Activity-inducible fusion proteins with heat shock protein 90 binding domain | 西雅图儿童医院以西雅图儿童研究机构名义经营 | 2023-12-05 | — | — | CN | disclosed |
| CN-114641475-A | Agricultural and horticultural insecticide or animal external or internal parasite control agent containing condensed heterocyclic compound having substituted cyclopropane oxadiazolyl group or salt thereof as active ingredient, and method for using same | 日本农药株式会社 | 2022-06-17 | — | — | CN | disclosed |
| CN-114501995-A | Agricultural and horticultural insecticide or animal external or internal parasite control agent containing substituted cyclopropane oxadiazolyl-containing imidazopyridazine compound or salt thereof as active ingredient, and method for using same | 日本农药株式会社 | 2022-05-13 | — | — | CN | disclosed |
| CN-110121500-B | 4H-pyrrolopyridine compound or salt thereof, agricultural or horticultural insecticide containing same, and method for using same | 日本农药株式会社 | 2022-05-03 | — | — | CN | disclosed |
| CN-110114354-B | Condensed heterocyclic compound having oxime group or salt thereof, agricultural and horticultural insecticide containing the same, and method of using the same | 日本农药株式会社 | 2022-04-29 | — | — | CN | disclosed |
| CN-114401967-A | Agricultural and horticultural insecticide or external or internal parasite control agent for animals containing imidazopyridazine compound or salt thereof as active ingredient, and method of use thereof | 日本农药株式会社 | 2022-04-26 | — | — | CN | disclosed |
| CN-114144419-A | Oxazepinotrienone derivative, agricultural or horticultural insecticide containing the derivative, and method of using the same | 日本农药株式会社 | 2022-03-04 | — | — | CN | disclosed |
| CN-113906024-A | Condensed heterocyclic compound having nitrogen atom at crosslinking portion or salt thereof, agricultural and horticultural insecticide containing the same, and method of using the same | 日本农药株式会社 | 2022-01-07 | — | — | CN | disclosed |
| CN-109415357-B | Condensed heterocyclic compound having hydrazone group or salt thereof, agricultural and horticultural insecticide containing the compound, and method for using the same | 日本农药株式会社 | 2021-10-29 | — | — | CN | disclosed |
| CN-109906221-B | N-alkylsulfonylindoline compound, agricultural and horticultural insecticide containing the same, and method of using the same | 日本农药株式会社 | 2021-10-01 | — | — | CN | disclosed |
| CN-109863150-B | 1H-pyrrolopyridine compound or N-oxide or salt thereof, agricultural or horticultural insecticide containing the compound, and method for using the same | 日本农药株式会社 | 2021-08-03 | — | — | CN | disclosed |
| CN-108290858-B | 3H-pyrrolopyridine compound or N-oxide thereof, or salt thereof, agricultural or horticultural insecticide containing the compound, and method for using the same | 日本农药株式会社 | 2021-07-06 | — | — | CN | disclosed |
| CN-108699050-B | Benzoxazole compound or salt thereof, agricultural and horticultural insecticide containing said compound, and method for using said insecticide | 日本农药株式会社 | 2021-06-11 | — | — | CN | disclosed |
| CN-108077275-B | Fungicidal penflufen mixtures | 朗盛德国有限责任公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-112384516-A | Benzimidazole compound having optionally halogenated alkylenedioxy group or salt thereof, agricultural or horticultural insecticide containing the same, and method of using the same | 日本农药株式会社 | 2021-02-19 | — | — | CN | disclosed |
| CN-108699066-B | Condensed heterocyclic compound having heterocyclic ring bonded thereto or salt thereof, agricultural or horticultural insecticide containing the same, and method of using the same | 日本农药株式会社 | 2020-12-22 | — | — | CN | disclosed |
| CN-108486024-B | Method for detecting organophosphorus pesticide by using sensing system based on flora | 上海交通大学 | 2020-12-11 | — | — | CN | disclosed |
| CN-107531622-B | Anthranilate compound or salt thereof, agricultural and horticultural bactericide containing anthranilate compound, and method for using same | 日本农药株式会社 | 2020-03-20 | — | — | CN | disclosed |
| US-7491738-B2 | Pest control agents | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-02-17 | — | — | US | disclosed |
| US-20060281780-A1 | Pest control agents | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281780-A1 | Pest control agents | CTRL, ACHE, DDT | ALDH1A1 3280/4885CYP3A4 1602/4885MAPK1 2022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.