Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1406399 | 0.72 | — | — | |
| SCHEMBL363383 | 0.64 | LMNA (0.45) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL56706 | 0.64 | ADRB1 (0.75) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| Water SCHEMBL28163332 | 0.62 | ADRB1 (0.72) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL27463408 | 0.62 | SIGMAR1 (0.43) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| Ammonia Solution, Strong SCHEMBL20512352 | 0.62 | ADRB1 (0.72) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| Hydrochloric Acid SCHEMBL11019815 | 0.62 | ADRB1 (0.72) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL27513171 | 0.62 | LMNA (0.43) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL5655247 | 0.62 | — | — | |
| SCHEMBL12495425 | 0.61 | LMNA (0.52) | SIGMAR1HTR3EHTR3BADRB1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445630-B2 | Polymers | BASF SE (DE) | 2013-05-21 | — | — | US | disclosed |
| EP-1858976-B1 | NOVEL POLYMERS | BASF SE (DE) | 2009-10-14 | — | — | EP | disclosed |
| US-20090105447-A1 | Novel Polymers | UDC IRELAND LIMITED (IE) | 2009-04-23 | — | — | US | disclosed |
| EP-1858976-A1 | NOVEL POLYMERS | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006097419-A1 | NOVEL POLYMERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-09-21 | — | — | WO | disclosed |
| US-4758263-A | 2-(2,5-difluorophenyl)-4-methyl-1,2,4-oxadiazolidine-3,5 diones | SANDOZ LTD. (CH) | 1988-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105447-A1 | Novel Polymers | PLEC, VIM, PUF60 | SIGMAR1 2375/4885HTR3E 3623/4885HTR3B 4109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.