SCHEMBL386178

SCHEMBL386178

OCCCCCCCCCCCCCCOO

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TSHR P16473 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 1/20 0.40
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
FFAR1 O14842 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
THRB P10828 1/20 0.35
HTT P42858 1/20 0.35
MAPT P10636 1/20 0.35
ACHE P22303 6/20 0.34
MAPK1 P28482 1/20 0.32
MIF P14174 1/20 0.31
LOX P28300 1/20 0.30
AOC3 Q16853 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29831 1.00 LMNA (0.40) LMNAMEN1KMT2ATSHRALDH1A1
SCHEMBL30879 1.00 LMNA (0.40) LMNAMEN1KMT2ATSHRALDH1A1
SCHEMBL30793 1.00 LMNA (0.40) LMNAMEN1KMT2ATSHRALDH1A1
SCHEMBL8928218 1.00 LMNA (0.40) LMNAMEN1KMT2ATSHRALDH1A1
SCHEMBL2801674 1.00 LMNA (0.40) LMNAMEN1KMT2ATSHRALDH1A1
SCHEMBL31034 1.00
SCHEMBL30759 1.00
SCHEMBL2795953 1.00 LMNA (0.40) LMNAMEN1KMT2ATSHRALDH1A1
SCHEMBL30599 0.97
SCHEMBL16595111 0.91 GAA (0.47) LMNAMEN1KMT2ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1969814-B Nasal administered preparation of melatonin INST PHARM & TOXICOLOGY AMMS 2010-05-26 CN claimed
CN-1969814-A Nasal administered preparation of melatonin POISON MED INST PLA MED ACAD (CN) 2007-05-30 CN claimed
US-5077199-A Comprising glucose oxidase free from catalase and nonionic surfactant stabilizer A. MENARINI S.A.S. (IT) 1991-12-31 US claimed
US-20240207411-A1 LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS SEAPORT THERAPEUTICS, INC. 2024-06-27 US disclosed
US-11975073-B2 Lipid prodrugs of neurosteroids PURETECH LYT, INC. (US) 2024-05-07 US disclosed
US-11938137-B2 Lipid prodrugs of mycophenolic acid and uses thereof PURETECH LYT, INC. (US) 2024-03-26 US disclosed
US-20240066436-A1 BIOBASED DEFOAMER COMPOSITIONS AND METHODS OF PREPARATION THEREOF KRATON CHEMICAL, LLC (US) 2024-02-29 US disclosed
US-20240050573-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2024-02-15 US disclosed
US-11883497-B2 Lymphatic system-directing lipid prodrugs PURETECH LYT, INC. (US) 2024-01-30 US disclosed
EP-4306524-A2 LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS PureTech LYT, Inc. (US) 2024-01-17 EP disclosed
US-20230416557-A1 ANTIFOG COMPOSITIONS AND ARTICLES MADE THEREOF Kraton Corporation (US) 2023-12-28 US disclosed
US-20120207818-A1 COMPOSITION FOR SUPPRESSING EXPRESSION OF TARGET GENE KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-08-16 US disclosed
US-8100135-B2 Hair coloring system and test device capable of being used in such a system L'OREAL S.A. (FR) 2012-01-24 US disclosed
EP-1648262-B1 HAIR COLORING SYSTEM AND TEST DEVICE CAPABLE OF BEING USED IN SUCH A SYSTEM OREAL (FR) 2009-07-29 EP disclosed
US-20070180895-A1 Hair coloring system and test device capable of being used in such a system L'OREAL S.A. (FR) 2007-08-09 US disclosed
US-20070179227-A1 VOC-free water reducible coating vehicles VOCFREE, INC. 2007-08-02 US disclosed
EP-1648262-A1 HAIR COLORING SYSTEM AND TEST DEVICE CAPABLE OF BEING USED IN SUCH A SYSTEM L'OREAL (FR) 2006-04-26 EP disclosed
US-20050148711-A1 VOC free water reducible coating vehicles VOCFREE, INC. 2005-07-07 US disclosed
WO-2005013759-A1 HAIR COLORING SYSTEM AND TEST DEVICE CAPABLE OF BEING USED IN SUCH A SYSTEM L'OREAL (FR) 2005-02-17 WO disclosed
EP-0422599-A1 Antigen-sensitized bead and use thereof Takeda Chemical Industries, Ltd. (JP) 1991-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11938137-B2 Lipid prodrugs of mycophenolic acid and uses thereof MALT1, CYP2B6, LIPA LMNA 4002/4885MEN1 1358/4885KMT2A 1823/4885
US-20240050573-A1 LYMPH DIRECTING PRODRUGS LTA, ABCB11, LYN LMNA 3766/4885MEN1 2306/4885KMT2A 4086/4885
US-11883497-B2 Lymphatic system-directing lipid prodrugs LIPA, MALT1, SGMS1 LMNA 2779/4885MEN1 1498/4885KMT2A 2872/4885
US-20240207411-A1 LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS LIPA, MALT1, SGMS1 LMNA 2779/4885MEN1 1498/4885KMT2A 2872/4885
US-11975073-B2 Lipid prodrugs of neurosteroids CYP21A2, CYP46A1, CYP17A1 LMNA 2962/4885MEN1 518/4885KMT2A 3097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.