Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29831 | 1.00 | LMNA (0.40) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL30879 | 1.00 | LMNA (0.40) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL30793 | 1.00 | LMNA (0.40) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL2801674 | 1.00 | LMNA (0.40) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL31034 | 1.00 | — | — | |
| SCHEMBL30759 | 1.00 | — | — | |
| SCHEMBL2795953 | 1.00 | LMNA (0.40) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL386178 | 1.00 | LMNA (0.40) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL30599 | 0.97 | — | — | |
| SCHEMBL16595111 | 0.91 | GAA (0.47) | LMNAMEN1KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698101-A | Hollow fiber membranes | MEMTEC LIMITED (AU) | 1997-12-16 | — | — | US | claimed |
| US-20240050573-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2024-02-15 | — | — | US | disclosed |
| US-11738087-B2 | Lymph directing prodrugs | MONASH UNIVERSITY (AU) | 2023-08-29 | — | — | US | disclosed |
| CN-115702171-A | Emulsion of di-sec-butyl peroxydicarbonate | 阿科玛法国公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-115667319-A | Organic peroxide emulsions with ethanol | 阿科玛法国公司 | 2023-01-31 | — | — | CN | disclosed |
| US-20220211664-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2022-07-07 | — | — | US | disclosed |
| US-11311512-B2 | Lymph directing prodrugs | MONASH UNIVERSITY (AU) | 2022-04-26 | — | — | US | disclosed |
| US-20190105299-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2019-04-11 | — | — | US | disclosed |
| US-20180243425-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2018-08-30 | — | — | US | disclosed |
| US-20170326103-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2017-11-16 | — | — | US | disclosed |
| EP-3180349-A1 | LYMPH DIRECTING PRODRUGS | Monash University (AU) | 2017-06-21 | — | — | EP | disclosed |
| EP-3027216-A1 | COMPOSITIONS AND PREPARATION METHODS OF LOW MELTING IONIC SALTS OF POORLY- WATER SOLUBLE DRUGS | MW Encap Limited (GB) | 2016-06-08 | — | — | EP | disclosed |
| US-20160151503-A1 | COMPOSITIONS AND PREPARATION METHODS OF LOW MELTING IONIC SALTS OF POORLY-WATER SOLUBLE DRUGS | MW ENCAP LIMITED (GB) | 2016-06-02 | — | — | US | disclosed |
| WO-2016023082-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2016-02-18 | — | — | WO | disclosed |
| CN-101484149-B | There is the pharmaceutical dosage form of the separate layer of multilamellar | EVONIK ROHM GMBH (DE) | 2015-12-02 | — | — | CN | disclosed |
| WO-2015013772-A1 | COMPOSITIONS AND PREPARATION METHODS OF LOW MELTING IONIC SALTS OF POORLY- WATER SOLUBLE DRUGS | MONASH UNIVERSITY (AU) | 2015-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240050573-A1 | LYMPH DIRECTING PRODRUGS | LTA, ABCB11, LYN | LMNA 3766/4885MEN1 2306/4885KMT2A 4086/4885 |
| US-20220211664-A1 | LYMPH DIRECTING PRODRUGS | LTA, ABCB11, LYN | LMNA 3766/4885MEN1 2306/4885KMT2A 4086/4885 |
| US-11311512-B2 | Lymph directing prodrugs | LTA, ABCB11, LYN | LMNA 3766/4885MEN1 2306/4885KMT2A 4086/4885 |
| US-20180243425-A1 | LYMPH DIRECTING PRODRUGS | MLNR, ABCB11, MLN | LMNA 3302/4885MEN1 832/4885KMT2A 3956/4885 |
| US-11738087-B2 | Lymph directing prodrugs | MLNR, ABCB11, MLN | LMNA 3302/4885MEN1 832/4885KMT2A 3956/4885 |
| US-20190105299-A1 | LYMPH DIRECTING PRODRUGS | LTA, ABCB11, LYN | LMNA 3766/4885MEN1 2306/4885KMT2A 4086/4885 |
| US-20170326103-A1 | LYMPH DIRECTING PRODRUGS | LTA, ABCB11, LYN | LMNA 3766/4885MEN1 2306/4885KMT2A 4086/4885 |
| US-20160151503-A1 | COMPOSITIONS AND PREPARATION METHODS OF LOW MELTING IONIC SALTS OF POORLY-WATER SOLUBLE DRUGS | ABCG2, SLC7A1, ABCB11 | LMNA 1172/4885MEN1 3730/4885KMT2A 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.