Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3859266 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TSHRGAARAB9AKDM4E | |
| SCHEMBL3861928 | 0.74 | MEN1 (0.47) | ALDH1A1RAB9AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3862153 | 0.74 | RAB9A (0.48) | ALDH1A1TSHRGAARAB9AKDM4E | |
| SCHEMBL16421474 | 0.67 | ALDH1A1 (0.50) | ALDH1A1TSHRGAARAB9AKDM4E | |
| SCHEMBL4936017 | 0.67 | ALDH1A1 (0.42) | ALDH1A1TSHRADORA3MEN1KMT2A | |
| SCHEMBL12677573 | 0.65 | TUBB4A (0.64) | ALDH1A1TSHRGAARAB9AKDM4E | |
| SCHEMBL8007448 | 0.64 | RAB9A (0.49) | ALDH1A1TSHRGAARAB9AKDM4E | |
| SCHEMBL10767069 | 0.63 | TSHR (0.66) | ALDH1A1TSHRGAARAB9AKDM4E | |
| SCHEMBL10697221 | 0.63 | TSHR (0.70) | ALDH1A1TSHRGAARAB9AKDM4E | |
| SCHEMBL7371883 | 0.63 | TOP1 (0.45) | ALDH1A1TSHRGAARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975597-B1 | QUINOLINE DERIVATIVES, HAVING IN PARTICULAR ANTIVIRAL PROPERTIES, PREPARATION AND BIOLOGICAL APPLICATIONS THEREOF | CENTRE NAT RECH SCIENT (FR) | 2009-09-02 | — | — | EP | disclosed |
| US-6670377-B1 | Inhibitory properties of human immunodeficiency virus integrase | CENTRE NATIONAL DE LA RECHERCHE (FR) | 2003-12-30 | — | — | US | disclosed |