Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TOP1 | P11387 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3859266 | 0.84 | ALDH1A1 (0.47) | RAB9AALDH1A1GAAKDM4ETSHR | |
| SCHEMBL9846447 | 0.75 | TLR8 (0.51) | RAB9ACNR2NPC1MAPTSMN1; SMN2 | |
| SCHEMBL3861931 | 0.74 | ALDH1A1 (0.41) | RAB9AALDH1A1GAAKDM4ETSHR | |
| SCHEMBL3860500 | 0.73 | HSD17B14 (0.52) | RAB9AALDH1A1GAAKDM4ETSHR | |
| SCHEMBL28605670 | 0.71 | CNR2 (0.62) | RAB9AALDH1A1GAAKDM4ETSHR | |
| SCHEMBL28438753 | 0.71 | HSD17B14 (0.51) | RAB9ACNR2KMT2ANPC1MEN1 | |
| SCHEMBL28443611 | 0.71 | MGAM (0.61) | RAB9AALDH1A1GAAKDM4ETSHR | |
| SCHEMBL9585344 | 0.71 | ALOX5 (0.48) | TSHRCNR2KMT2AMGAM | |
| SCHEMBL3862150 | 0.70 | GLA (0.67) | RAB9AALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL9756946 | 0.70 | CYSLTR2 (0.45) | RAB9AALDH1A1KDM4ECNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975597-B1 | QUINOLINE DERIVATIVES, HAVING IN PARTICULAR ANTIVIRAL PROPERTIES, PREPARATION AND BIOLOGICAL APPLICATIONS THEREOF | CENTRE NAT RECH SCIENT (FR) | 2009-09-02 | — | — | EP | disclosed |
| US-6670377-B1 | Inhibitory properties of human immunodeficiency virus integrase | CENTRE NATIONAL DE LA RECHERCHE (FR) | 2003-12-30 | — | — | US | disclosed |
| EP-0975597-A1 | QUINOLINE DERIVATIVES, HAVING IN PARTICULAR ANTIVIRAL PROPERTIES, PREPARATION AND BIOLOGICAL APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998045269-A1 | QUINOLINE DERIVATIVES, HAVING IN PARTICULAR ANTIVIRAL PROPERTIES, PREPARATION AND BIOLOGICAL APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1998-10-15 | — | — | WO | disclosed |