Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | PPARG | P37231 | 10/20 | 0.60 |
| ▸ | PPARA | Q07869 | 10/20 | 0.60 |
| ▸ | PPARD | Q03181 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3862851 | 1.00 | ALDH1A1 (0.66) | ALDH1A1MAPTPPARGPPARAPPARD | |
| SCHEMBL13651556 | 0.88 | PPARG (0.60) | ALDH1A1MAPTPPARGPPARAPPARD | |
| SCHEMBL20117226 | 0.84 | JAK3 (0.53) | ALDH1A1MAPTPPARGPPARAPPARD | |
| SCHEMBL6658424 | 0.84 | KMT2A (0.56) | ALDH1A1MAPTPPARGPPARAPPARD | |
| SCHEMBL4710388 | 0.83 | MAPT (0.60) | ALDH1A1MAPTPPARGPPARAPPARD | |
| SCHEMBL24779267 | 0.83 | PPARA (0.54) | ALDH1A1MAPTPPARGPPARAPPARD | |
| SCHEMBL28767088 | 0.83 | PPARA (0.54) | ALDH1A1MAPTPPARGPPARAPPARD | |
| SCHEMBL7542832 | 0.81 | PPARA (0.65) | ALDH1A1PPARGPPARAPPARDKLK5 | |
| SCHEMBL7542840 | 0.81 | PPARA (0.65) | ALDH1A1PPARGPPARAPPARDKLK5 | |
| SCHEMBL25464652 | 0.80 | CYP1A2 (0.62) | ALDH1A1MAPTPPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | Changzhou University (CN) | 2023-11-30 | — | — | US | disclosed |
| US-20090253166-A1 | Conjugation of Peptides | NOVO NORDISK A/S (DK) | 2009-10-08 | — | — | US | disclosed |
| US-7524813-B2 | Selectively conjugated peptides and methods of making the same | NOVO NORDISK HEALTH CARE AG (CH) | 2009-04-28 | — | — | US | disclosed |
| US-20070111926-A1 | Conjugation of peptides | NOVO NORDISK A/S (DK) | 2007-05-17 | — | — | US | disclosed |
| EP-1673464-A2 | CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005035553-A2 | CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2005-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | PTMS, CBS, CHAMP1 | ALDH1A1 1808/4885MAPT 2383/4885PPARG 3449/4885 |
| US-20070111926-A1 | Conjugation of peptides | DNPEP, ENPEP, ANPEP | ALDH1A1 2226/4885MAPT 4410/4885PPARG 4518/4885 |
| US-20090253166-A1 | Conjugation of Peptides | DNPEP, ENPEP, ANPEP | ALDH1A1 2226/4885MAPT 4410/4885PPARG 4518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.