Sugi Predict

Sugi Predict / Compounds / SCHEMBL3864585

SCHEMBL3864585

SCHEMBL3864585

CC(=O)O[C@@H](C=O)[C@H](O)[C@H](O)CO

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ PDE4A P27815 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ USP2 O75604 1/20 0.34
▸ SLCO1B1 Q9Y6L6 1/20 0.34
▸ TSHR P16473 2/20 0.33
▸ AKR1B1 P15121 1/20 0.33
▸ KDM4E B2RXH2 2/20 0.32
▸ CHRM2 P08172 1/20 0.31
▸ CHRM4 P08173 1/20 0.31
▸ CHRM1 P11229 1/20 0.31
▸ TBXA2R P21731 1/20 0.31
▸ PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7068618 1.00 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL7144047 1.00 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL6870720 1.00 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL27671076 1.00 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL626496 1.00 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL9734750 0.98 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL14808559 0.96 LMNA (0.39) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL92768 0.94 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL2015790 0.94 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL215095 0.94 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118420693-A 6- (Isopropyl disulfide) -guanosine compound, and preparation method and application thereof 浙江大学金华研究院 2024-08-02 — — CN claimed
CN-114276393-A Preparation process of beta-nicotinamide riboside chloride 南京诺云生物科技有限公司 2022-04-05 — — CN claimed
CN-118420693-A 6- (Isopropyl disulfide) -guanosine compound, and preparation method and application thereof 浙江大学金华研究院 2024-08-02 — — CN disclosed
CN-117940567-A Antisense compounds that modulate the expression of WFDC2 克迈恩有限公司 2024-04-26 — — CN disclosed
CN-113755415-B Novel recombinant microorganism with NMN synthesis path and production method thereof 苏州华赛生物工程技术有限公司 2024-03-29 — — CN disclosed
CN-113755413-B Recombinant microorganism for producing beta-nicotinamide mononucleotide and method for producing NMN by using same 苏州华赛生物工程技术有限公司 2023-09-05 — — CN disclosed
CN-114807078-B Method for biosynthesis of NMN 四川盈嘉合生科技有限公司 2023-09-01 — — CN disclosed
CN-113755411-B Recombinant microorganism for high-yield of beta-nicotinamide mononucleotide and method for producing beta-nicotinamide mononucleotide by recombinant microorganism 苏州华赛生物工程技术有限公司 2023-08-01 — — CN disclosed
CN-112961890-B Enzymatic synthesis method of nicotinamide mononucleotide 深圳希吉亚生物技术有限公司 2023-06-27 — — CN disclosed
CN-111676204-B Nicotinamide phosphoribosyl transferase for preparing nicotinamide mononucleotide, coding gene, vector and application 成都及禾生物科技有限公司 2023-05-23 — — CN disclosed
CN-110590879-B Acridinone derivatives containing ribose or deoxyribose sugar structure and preparation method and application thereof 河南师范大学 2022-12-27 — — CN disclosed
CN-111676204-A Nicotinamide phosphoribosyl transferase for preparing nicotinamide mononucleotide, coding gene, carrier and application 成都及禾生物科技有限公司 2020-09-18 — — CN disclosed
CN-109666658-B Nicotinamide phosphoribosyl transferase for preparing NMN, coding gene, recombinant vector and application 成都及禾生物科技有限公司 2020-08-04 — — CN disclosed
US-7521432-B2 Compositions and methods for identifying agents which regulate chromosomal stability, gene activation and aging WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2009-04-21 — — US disclosed
US-7291606-B2 Compositions and methods for identifying agents which regulate chromosomal stability, gene activation and aging WISCONSON ALUMNI RESEARCH FOUNDATION (US) 2007-11-06 — — US disclosed
US-20070255045-A1 COMPOSITIONS AND METHODS FOR IDENTIFYING AGENTS WHICH REGULATE CHROMOSOMAL STABILITY, GENE ACTIVATION AND AGING WISCONSIN ALUMNI RESEARCH FOUNDATION 2007-11-01 — — US disclosed
US-20070225246-A1 O-acetyl-ADP-ribose non-hydrolyzable analogs NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-09-27 — — US disclosed
WO-2005016878-A2 METHODS FOR THE PREPARATION OF 5-FLUORO-PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 2005-02-24 — — WO disclosed
US-20040067228-A1 Compositions and methods for identifying agents which regulate chromosomal stability, gene activation and aging WISCONSIN ALUMNI RESEARCH FOUNDATION 2004-04-08 — — US disclosed
WO-2002038579-A1 COMPOSITIONS AND METHODS FOR IDENTIFYING AGENTS WHICH REGULATE CHROMOSOMAL STABILITY, GENE ACTIVATION AND AGING OREGON HEALTH & SCIENCE UNIVERSITY (US) 2002-05-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070225246-A1 O-acetyl-ADP-ribose non-hydrolyzable analogs PARP1, TIPARP, CD38 LMNA 1670/4885L3MBTL1 1225/4885PDE4A 2188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.