Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3864585 | 1.00 | LMNA (0.37) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL7068618 | 1.00 | LMNA (0.37) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL6870720 | 1.00 | LMNA (0.37) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL27671076 | 1.00 | LMNA (0.37) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL626496 | 1.00 | LMNA (0.37) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL9734750 | 0.98 | LMNA (0.36) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL14808559 | 0.96 | LMNA (0.39) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL92768 | 0.94 | LMNA (0.41) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL2015790 | 0.94 | LMNA (0.41) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL215095 | 0.94 | LMNA (0.41) | LMNAL3MBTL1PDE4ATDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027359-B9 | MONOCYCLIC L-NUCLEOSIDES, ANALOGS AND USES THEREOF | RIBAPHARM INC (US) | 2003-09-17 | — | — | EP | disclosed |
| EP-1027359-B1 | MONOCYCLIC L-NUCLEOSIDES, ANALOGS AND USES THEREOF | RIBAPHARM INC (US) | 2003-04-23 | — | — | EP | disclosed |
| US-6552183-B1 | Moncyclic L-nucleosides analogs | ICN PHARMACEUTICALS, INC. | 2003-04-22 | — | — | US | disclosed |
| EP-1132393-B1 | L-Ribavirin and uses thereof | ICN PHARMACEUTICALS (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-1254911-A1 | Monocyclic L-nucleosides, analogs and uses thereof | ICN Pharmaceuticals, Inc. (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1132393-A1 | L-Ribavirin and uses thereof | ICN Pharmaceuticals, Inc. (US) | 2001-09-12 | — | — | EP | disclosed |