SCHEMBL6870720

SCHEMBL6870720

CC(=O)O[C@H](C=O)[C@H](O)[C@H](O)CO

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PDE4A P27815 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
TSHR P16473 2/20 0.33
AKR1B1 P15121 1/20 0.33
KDM4E B2RXH2 2/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3864585 1.00 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL7068618 1.00 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL7144047 1.00 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL27671076 1.00 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL626496 1.00 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL9734750 0.98 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL14808559 0.96 LMNA (0.39) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL92768 0.94 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL2015790 0.94 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL215095 0.94 LMNA (0.41) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6812037-B1 INCLUDING SARCODICTYIN A AND ELEUTHEROBIN; OBTAINED FROM ORGANISMS OF ORDER GORGONACEA (CORAL); IN VITRO CYTOTOXICITY THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2004-11-02 US disclosed
US-20030207407-A1 Corn fiber for the production of advanced chemicals and materials: derivatizable cellulose and cellulose derivatives made therefrom EASTMAN CHEMICAL COMPANY 2003-11-06 US disclosed
US-20030199087-A1 Methods of separating a corn fiber lipid fraction from corn fiber EASTMAN CHEMICAL COMPANY 2003-10-23 US disclosed
US-20030188340-A1 Methods of separating a corn fiber lipid fraction from corn fiber EASTMAN CHEMICAL COMPANY 2003-10-02 US disclosed
US-6589760-B1 Having phytosterol esters and phytosterols; using amylase and protease for destarching and proteolysis; solvent extraction EASTMAN CHEMICAL COMPANY 2003-07-08 US disclosed
US-6586212-B1 Heating with a liquid, contacting with a protease enzyme and alkaline extractant; separating the liquid comprising arabinoxylan; utilizing the components to generate valuable products EASTMAN CHEMICAL COMPANY 2003-07-01 US disclosed
EP-1232170-A1 ANTIMITOTIC COMPOUNDS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2002-08-21 EP disclosed
US-6388069-B1 HEATING AQUEOUS MIXTURE OF CORN FIBER AND LIQUID, CONTACTING WITH PROTEASE, SEPARATING, CONTACTING WITH ALKALINE EXTRACTANT TO FORM INSOLUBLE CELLULOSE AND LIQUID WITH ARABINOGLYCAN, SEPARATING, CONCENTRATING LIQUID EASTMAN CHEMICAL COMPANY 2002-05-14 US disclosed
US-6352845-B1 FORMING MONOSACCHARIDE BY HYDROLYSIS EASTMAN CHEMICAL COMPANY 2002-03-05 US disclosed
EP-1155104-A2 CORN FIBER FOR THE PRODUCTION OF ADVANCED CHEMICALS AND MATERIALS EASTMAN CHEMICAL COMPANY (US) 2001-11-21 EP disclosed
WO-2000047701-A9 CORN FIBER FOR THE PRODUCTION OF ADVANCED CHEMICALS AND MATERIALS EASTMAN CHEM CO (US) 2001-10-25 WO disclosed
US-20010020091-A1 Corn fiber for the production of advanced chemicals and materials: arabinoxylan and arabinoxylan derivatives prepared therefrom EASTMAN CHEMICAL COMPANY 2001-09-06 US disclosed
WO-2001038339-A1 ANTIMITOTIC COMPOUNDS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2001-05-31 WO disclosed
WO-2000047701-A2 CORN FIBER FOR THE PRODUCTION OF ADVANCED CHEMICALS AND MATERIALS EASTMAN CHEMICAL COMPANY (US) 2000-08-17 WO disclosed
WO-1999029704-A1 A SYNTHETIC PROCESS TOWARD TOTAL SYNTHESIS OF ELEUTHERUBIN AND ITS ANALOGUES AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1999-06-17 WO disclosed