SCHEMBL38652136

SCHEMBL38652136

Cc1ccc(NC(=O)c2cccc(=O)n2O)c(C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.53
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
RAB9A P51151 4/20 0.48
NPC1 O15118 2/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 3/20 0.48
PKM P14618 1/20 0.48
HPGD P15428 2/20 0.47
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
TAS1R2 Q8TE23 1/20 0.47
GAA P10253 1/20 0.46
ATM Q13315 1/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 1/20 0.46
HTT P42858 1/20 0.46
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38652013 0.83 IDH1 (0.55) IDH1LMNAPKMSMN1; SMN2ALDH1A1
SCHEMBL22852019 0.79 IDH1 (0.66) IDH1MEN1KMT2ARAB9ANPC1
SCHEMBL38651960 0.76 THRB (0.47) MEN1KMT2ARAB9ANPC1LMNA
SCHEMBL22852085 0.76 IDH1 (0.62) IDH1RAB9ANPC1GAAALDH1A1
SCHEMBL38651962 0.72 IDH1 (0.61) IDH1MEN1KMT2ARAB9ANPC1
SCHEMBL4449040 0.72 TAS1R3 (0.69) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL7188546 0.72 MAPT (0.65) MEN1KMT2ARAB9ANPC1LMNA
SCHEMBL8820818 0.71 MAPT (0.71) MEN1KMT2ARAB9ANPC1LMNA
SCHEMBL38651963 0.71 IDH1 (0.64) IDH1MEN1KMT2ALMNAHPGD
SCHEMBL12388857 0.71 TAS1R3 (0.71) MEN1KMT2ARAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010834-A Piroctone derivative, and preparation method and application thereof 中国海洋大学 2026-05-12 CN disclosed