SCHEMBL38660957

SCHEMBL38660957

CC(NC(=O)N1CCOc2ncccc21)c1cccc(F)c1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 7/20 0.42
LCK P06239 2/20 0.42
MET P08581 2/20 0.42
KDR P35968 2/20 0.42
TEK Q02763 1/20 0.42
KIT P10721 6/20 0.42
LIPG Q9Y5X9 1/20 0.42
KCNK3 O14649 1/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PRKG1 Q13976 1/20 0.40
MAPK1 P28482 1/20 0.39
ROCK1 Q13464 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38662454 0.89 LCK (0.40) ROCK2LCKMETKDRTEK
SCHEMBL38661257 0.89 KCNK3 (0.44) LCKMETKDRTEKKIT
SCHEMBL38662920 0.83 MAPT (0.53) LCKMETKDRTEKKCNK3
SCHEMBL38663492 0.83 P2RX3 (0.41) LCKMETKDRTEKLIPG
SCHEMBL31078071 0.77 MAPK1 (0.43) ROCK2KITPRKG1MAPK1ROCK1
SCHEMBL38661847 0.77 RIPK1 (0.54)
SCHEMBL31077935 0.76 HTT (0.56)
SCHEMBL30491808 0.70 GRM5 (0.43)
SCHEMBL38662176 0.68 MAPT (0.49) LCKMETKDRTEK
SCHEMBL16897934 0.68 DRD2 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036749-A Aryl morpholine ring compound and application thereof 成都赜灵生物医药科技股份有限公司 2026-05-15 CN disclosed