Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 13/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3866264 | 0.82 | CA12 (0.57) | ALDH1A1SMN1; SMN2GLAHPGDALOX12 | |
| SCHEMBL5119014 | 0.80 | MAPT (0.50) | ALDH1A1SMN1; SMN2GLAHPGDMAPT | |
| SCHEMBL5119021 | 0.80 | MAPT (0.50) | ALDH1A1SMN1; SMN2GLAHPGDMAPT | |
| SCHEMBL4953837 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2GLAHPGDALOX12 | |
| SCHEMBL7938661 | 0.79 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2GLAHPGDALOX12 | |
| SCHEMBL14089668 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GLAHPGDALOX12 | |
| SCHEMBL14117517 | 0.79 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2GLAHPGDALOX12 | |
| SCHEMBL18549022 | 0.79 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2GLAHPGDALOX12 | |
| SCHEMBL5157922 | 0.79 | PRSS1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL6673456 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2GLAHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070011827-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with at least one group chosen from hydroxyl, alkoxy, and/or amino groups and method of dyeing keratinous fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011827-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with at least one group chosen from hydroxyl, alkoxy, and/or amino groups and method of dyeing keratinous fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739075-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with one or more hydroxyl, alkoxy and/or amino groups and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011827-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with at least one group chosen from hydroxyl, alkoxy, and/or amino groups and method of dyeing keratinous fibers | KRT18, PLOD3, DSP | ALDH1A1 298/4885SMN1; SMN2 4570/4885GLA 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.