SCHEMBL38664283

SCHEMBL38664283

COc1cc(Br)cc2c(I)n[nH]c12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1B Q9Y463 2/20 0.35
NQO2 P16083 2/20 0.35
ERN1 O75460 2/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
MAPT P10636 2/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 2/20 0.33
PRNP P04156 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
AXL P30530 1/20 0.33
EIF2AK1 Q9BQI3 1/20 0.32
AMY1A P0DUB6 2/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
ITK Q08881 1/20 0.31
MAPK1 P28482 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
GAA P10253 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20487931 0.80 GSK3B (0.34) DYRK1BNQO2
SCHEMBL14030589 0.78 ALDH1A1 (0.33) DYRK1BMAPTALDH1A1GAA
SCHEMBL38664280 0.77 CHEK1 (0.39) DYRK1B
SCHEMBL26204533 0.77 CHEK1 (0.39) DYRK1B
SCHEMBL18130787 0.75 NR4A2 (0.43) MAPTALDH1A1MAPK1GAA
SCHEMBL38661124 0.75 PDPK1 (0.31)
SCHEMBL20488776 0.75
SCHEMBL30993046 0.75 GABRA1 (0.40)
SCHEMBL31313135 0.75 MAP3K7 (0.37) NQO2ERN1ALOX15ALOX12MAPT
SCHEMBL5484683 0.74 KDM4E (0.53) NQO2MAPTLMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101971-A2 EGFR INHIBITORS FOR TREATING DISEASE BLOSSOMHILL THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed