Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | PGR | P06401 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13937138 | 1.00 | ESR1 (0.62) | ESR1SLC6A4CYP2C19LMNAPGR | |
| SCHEMBL2168891 | 0.82 | ESR1 (0.59) | ESR1SLC6A4CYP2C19LMNAPGR | |
| SCHEMBL13937137 | 0.81 | LMNA (0.40) | ESR1SLC6A4CYP2C19LMNAPGR | |
| SCHEMBL3866941 | 0.81 | LMNA (0.40) | ESR1SLC6A4CYP2C19LMNAPGR | |
| SCHEMBL11332158 | 0.81 | ALOX15 (0.71) | ESR1SLC6A4CYP2C19LMNAPGR | |
| SCHEMBL13918068 | 0.80 | ESR1 (0.58) | ESR1SLC6A4CYP2C19LMNAPGR | |
| SCHEMBL7753698 | 0.80 | ESR1 (0.69) | ESR1SLC6A4CYP2C19LMNAPGR | |
| SCHEMBL14702188 | 0.78 | ABCB11 (0.70) | ESR1SLC6A4CYP2C19LMNAPGR | |
| SCHEMBL3402721 | 0.78 | ABCB11 (0.70) | ESR1SLC6A4CYP2C19LMNAPGR | |
| SCHEMBL14363178 | 0.78 | ESR1 (0.77) | ESR1SLC6A4CYP2C19LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027141-A1 | 11BETA-BENZALDOXIME DERIVATIVES OF D-HOMOOESTRA-4,9-DIEN-3-ONES | Bayer Schering Pharma AG (DE) | 2009-02-25 | — | — | EP | disclosed |
| US-7473709-B2 | 11β-benzaldoxime derivatives of D-homooestra-4,9-dien-3-ones | BAYER SCHERING PHARMA AG (DE) | 2009-01-06 | — | — | US | disclosed |
| US-20070149621-A1 | 11Beta-benzaldoxime derivatives of D-homooestra-4,9-dien-3-ones | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | US | disclosed |
| WO-2007065726-A1 | 11β-BENZALDOXIME DERIVATIVES OF D-HOMOOESTRA-4,9-DIEN-3-ONES | BAYER SCHERING PHARMA AG (DE) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149621-A1 | 11Beta-benzaldoxime derivatives of D-homooestra-4,9-dien-3-ones | HSD17B13, HSD17B7, HSD17B11 | ESR1 72/4885SLC6A4 3262/4885CYP2C19 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.