Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3872027 | 0.81 | ADRB2 (0.48) | ADRB2MAPTMAPK1PIK3R2HPGD | |
| SCHEMBL2711291 | 0.78 | ADRB2 (0.65) | ADRB2MAPTMAPK1PIK3R2HPGD | |
| SCHEMBL3867390 | 0.78 | PIK3R2 (0.55) | ADRB2MAPTMAPK1PIK3R2 | |
| SCHEMBL3869429 | 0.77 | ALDH1A1 (0.49) | MAPTMAPK1HPGD | |
| SCHEMBL2710931 | 0.70 | NT5E (0.48) | MAPTHPGD | |
| SCHEMBL895026 | 0.68 | ADRB2 (0.64) | ADRB2MAPTMAPK1HPGDADRA2A | |
| SCHEMBL14136437 | 0.66 | ADRB2 (0.58) | ADRB2MAPK1HPGDADRA2AHTR2C | |
| SCHEMBL11836535 | 0.66 | NT5E (0.46) | PIK3R2HPGD | |
| SCHEMBL2711485 | 0.66 | MAP4K4 (0.41) | HPGDHRH1HTR2BADORA2AADORA1 | |
| SCHEMBL11831604 | 0.66 | NR4A2 (0.41) | PIK3R2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601355-B2 | Compositions and methods for altering immune function | NORTHWESTERN UNIVERSITY (US) | 2009-10-13 | — | — | US | disclosed |
| US-7601355-B2 | Compositions and methods for altering immune function | NORTHWESTERN UNIVERSITY (US) | 2009-10-13 | — | — | US | disclosed |
| US-7601355-B2 | Compositions and methods for altering immune function | NORTHWESTERN UNIVERSITY (US) | 2009-10-13 | — | — | US | disclosed |
| US-20070041981-A1 | Compositions and methods for altering immune function | NORTHWESTERN UNIVERSITY | 2007-02-22 | — | — | US | disclosed |
| US-20070041981-A1 | Compositions and methods for altering immune function | NORTHWESTERN UNIVERSITY | 2007-02-22 | — | — | US | disclosed |
| US-20070041981-A1 | Compositions and methods for altering immune function | NORTHWESTERN UNIVERSITY | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070041981-A1 | Compositions and methods for altering immune function | IL2, ICOS, IFNG | ADRB2 2549/4885MAPT 4334/4885MAPK1 3796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.