Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912395 | 0.84 | CPA1 (0.45) | CPA1MGAMGAASIMGAM2 | |
| SCHEMBL1228652 | 0.84 | CPA1 (0.45) | CPA1MGAMGAASIMGAM2 | |
| SCHEMBL1410099 | 0.84 | CPA1 (0.45) | CPA1MGAMGAASIMGAM2 | |
| SCHEMBL29021054 | 0.76 | KDM4E (0.36) | CPA1MGAMGAASIMGAM2 | |
| SCHEMBL17674185 | 0.74 | L3MBTL1 (0.45) | L3MBTL1KMT2APOLBCYP1A2MGAM | |
| SCHEMBL25295269 | 0.73 | L3MBTL1 (0.47) | L3MBTL1KMT2APOLBCYP1A2MGAM | |
| SCHEMBL1664773 | 0.73 | MAPT (0.38) | CPA1L3MBTL1POLBCYP1A2MGAM | |
| SCHEMBL3121387 | 0.73 | KDM4E (0.39) | CPA1MGAMGAASIMGAM2 | |
| SCHEMBL18775322 | 0.72 | CPA1 (0.44) | CPA1 | |
| SCHEMBL103981 | 0.72 | L3MBTL1 (0.53) | L3MBTL1KMT2APOLBCYP1A2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127560-A1 | INTERMEDIATES FOR THE PREPARATION OF PREGABALIN AND PROCESS FOR THEIR PREPARATION | CHEMO IBÉRICA, S.A. (ES) | 2009-10-22 | — | — | WO | disclosed |
| EP-2110372-A1 | Intermediates for the preparation of Pregabalin and process for their preparation | Chemo Ibérica, S.A. (ES) | 2009-10-21 | — | — | EP | disclosed |
| WO-2009053446-A2 | PREGABALIN INTERMEDIATES AND PROCESS FOR PREPARING THEM AND PREGABALIN | CHEMO IBÉRICA, S.A. (ES) | 2009-04-30 | — | — | WO | disclosed |
| EP-2053040-A1 | Pregabalin intermediates and process for preparing them and Pregabalin | Chemo Ibérica, S.A. (ES) | 2009-04-29 | — | — | EP | disclosed |
| US-7141695-B2 | Methods for producing substituted acrylic acid esters and use of the latter for producing substituted γ-amino acids | GRUNENTHAL GMBH (DE) | 2006-11-28 | — | — | US | disclosed |
| US-20050043565-A1 | Methods for producing substituted acrylic acid esters and use of the latter for producing substituted $G (G)-amino acids | GRUNENTHAL GMBH (DE) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043565-A1 | Methods for producing substituted acrylic acid esters and use of the latter for producing substituted $G (G)-amino acids | GLUL, SUCLG2, RIMKLA | CPA1 3568/4885L3MBTL1 3517/4885KMT2A 3149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.