Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3864827 | 0.98 | FFAR1 (0.44) | TRPA1DDAH1GAPDHMAPTFFAR1 | |
| SCHEMBL3868756 | 0.86 | CHRM1 (0.33) | NFKB1FAAHMEN1TP53CYP1A2 | |
| SCHEMBL1784022 | 0.85 | TRPA1 (0.48) | TRPA1DDAH1GAPDHMAPTFFAR1 | |
| SCHEMBL1784024 | 0.85 | TRPA1 (0.48) | TRPA1DDAH1GAPDHMAPTFFAR1 | |
| SCHEMBL943388 | 0.83 | FFAR1 (0.47) | TRPA1DDAH1GAPDHMAPTFFAR1 | |
| SCHEMBL3508071 | 0.81 | LAP3 (0.40) | MAPTFFAR1GPR84LCKPPARD | |
| SCHEMBL7636971 | 0.81 | GPR84 (0.50) | TRPA1DDAH1GAPDHMAPTFFAR1 | |
| SCHEMBL7747945 | 0.81 | GPR84 (0.50) | TRPA1DDAH1GAPDHMAPTFFAR1 | |
| SCHEMBL3729898 | 0.81 | GPR84 (0.50) | TRPA1DDAH1GAPDHMAPTFFAR1 | |
| SCHEMBL1412474 | 0.81 | LCK (0.44) | MAPTFFAR1FFAR4GPR84LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367766-B2 | Tire with a component made of a rubber composition comprised of a rubber having pendant hydroxyl groups and a nonsulfur containing silane | GOODYEAR TIRE & RUBBER COMPANY, THE | 2013-02-05 | — | — | US | disclosed |
| US-20090088520-A1 | TIRE WITH A COMPONENT MADE OF A RUBBER COMPOSITION COMPRISED OF A RUBBER HAVING PENDANT HYDROXYL GROUPS AND A NONSULFUR CONTAINING SILANE | THE GOODYEAR TIRE & RUBBER COMPANY | 2009-04-02 | — | — | US | disclosed |
| US-7476708-B2 | Tire with a component made of a rubber composition comprised of a rubber having pendant hydroxyl groups and a nonsulfur containing silane | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2009-01-13 | — | — | US | disclosed |
| US-20080153985-A1 | Tire with a component made of a rubber composition comprised of a rubber having pendant hydroxyl groups and a nonsulfur containing silane | THE GOODYEAR TIRE & RUBBER COMPANY | 2008-06-26 | — | — | US | disclosed |
| EP-1935936-A2 | Rubber composition comprising a rubber having pendant hydroxyl groups and a nonsulfur containing silane | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-1930184-A1 | Tire with apex containing in-situ resin and rubber with pendant hydroxyl groups | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-06-11 | — | — | EP | disclosed |
| US-20080115874-A1 | Tire with apex containing in-situ resin and rubber with pendant hydroxyl groups | THIELEN GEORGES MARCEL VICTOR | 2008-05-22 | — | — | US | disclosed |
| US-7294666-B2 | Tire with component of rubber composition comprised of silica reinforcement and emulsion polymerization derived terpolymer rubber of diene/vinyl aromatic compound which contains pendant hydroxyl groups | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2007-11-13 | — | — | US | disclosed |
| EP-1308318-B1 | Tire with a component made of a rubber composition comprised of a rubber having pendant hydroxyl groups and a rubber containing nitrile moiety | GOODYEAR TIRE & RUBBER (US) | 2007-09-12 | — | — | EP | disclosed |
| US-6716925-B2 | A BLENDS COMPRISING AT LEAST TWO TERPOLYMERS, BOTH CONSISTS OF A CONJUGATED DIENE MONOMER, VINYL AROMATIC MONOMER; MOONEY VISCOSITY, TEAR RESISTANCE, TENSILE STRENGTH, ELONGATION | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-04-06 | — | — | US | disclosed |
| US-20030125468-A1 | Tire with a component made of a rubber composition comprised of a rubber having pendant hydroxyl groups and a rubber containing a nitrile moiety | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-07-03 | — | — | US | disclosed |
| EP-1308318-A2 | Tire with a component made of a rubber composition comprised of a rubber having pendant hydroxyl groups and a rubber containing nitrile moiety | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2003-05-07 | — | — | EP | disclosed |
| US-20020173560-A1 | Tire with component of rubber composition comprised of silica reinforcement and emulsion polymerization derived terpolymer rubber of diene/vinyl aromatic compound which contains pendant hydroxyl groups | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-11-21 | — | — | US | disclosed |
| EP-1241204-A1 | Tire with component of rubber composition comprised of silica reinforcement and emulsion polymerization derived terpolymer rubber of diene/vinyl aromatic compound which contains pendant hydroxyl groups | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-09-18 | — | — | EP | disclosed |