SCHEMBL3869028

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12549629	0.80	TNKS (1.00)	TNKSTNKS2LMNAPOLBKDM4E
	SCHEMBL12791230	0.79	LMNA (0.72)	TNKSTNKS2LMNAPOLBKDM4E
	SCHEMBL6520217	0.78	KMT2A (0.71)	TNKSTNKS2LMNAPOLBKDM4E
	SCHEMBL15462269	0.77	TNKS (0.61)	TNKSTNKS2LMNAPOLBKDM4E
	SCHEMBL12549503	0.77	TNKS (0.59)	TNKSTNKS2LMNAPOLBKDM4E
	SCHEMBL24031096	0.76	HDAC1 (0.76)	TP53HDAC1HDAC11HDAC8HDAC6
	SCHEMBL6520182	0.75	POLB (0.69)	TNKSTNKS2LMNAPOLBKDM4E
	SCHEMBL12791473	0.73	MEN1 (0.55)	TNKSTNKS2LMNAPOLBKDM4E
	SCHEMBL11960890	0.72	MAPK10 (0.63)	TNKSTNKS2LMNAPOLBKDM4E
	SCHEMBL11961159	0.70	TSHR (0.61)	TNKSTNKS2LMNAPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.