SCHEMBL3869807

SCHEMBL3869807

Cc1ccsc1C1=C(c2nc(-c3ccccc3)sc2C)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RARA P10276 2/20 0.41
▸ RARB P10826 2/20 0.41
▸ RARG P13631 2/20 0.41
▸ APEX1 P27695 1/20 0.41
▸ KDM4E B2RXH2 3/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ CYP3A4 P08684 2/20 0.41
▸ CYP2C19 P33261 2/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ CYP1A2 P05177 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ CYP2E1 P05181 1/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ CYP2A6 P11509 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ CYP2B6 P20813 1/20 0.38
▸ ATP4A P20648 2/20 0.36
▸ ATP4B P51164 2/20 0.36
▸ NISCH Q9Y2I1 1/20 0.35
▸ PDPK1 O15530 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3434571 0.87 RARA (0.51) RARARARBRARGAPEX1KDM4E
SCHEMBL3869530 0.81 RARA (0.40) RARARARBRARGAPEX1KDM4E
SCHEMBL3869213 0.78 ROCK1 (0.48) RARARARBRARGAPEX1ATP4A
SCHEMBL3872932 0.78 ROCK1 (0.39) RARARARBRARGAPEX1KDM4E
SCHEMBL3879140 0.78 RARA (0.37) RARARARBRARGAPEX1KDM4E
SCHEMBL3869752 0.78 RARA (0.40) RARARARBRARGAPEX1KDM4E
SCHEMBL3849652 0.76 CYP2A6 (0.42) KDM4EALDH1A1CYP3A4CYP2C19MEN1
SCHEMBL3872128 0.75 RARA (0.41) RARARARBRARGAPEX1KDM4E
SCHEMBL14838337 0.75 PTGS2 (0.46) KDM4EALDH1A1CYP3A4CYP2C19CYP1A2
SCHEMBL4917690 0.73 PTGDR2 (0.40) RARARARBRARGAPEX1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11609442-B2 System and method for customization of a photochromic article TRANSITIONS OPTICAL, LTD. (IE) 2023-03-21 — — US disclosed
US-20210055575-A1 System and Method for Customization of a Photochromic Article TRANSITIONS OPTICAL, LTD. (IE) 2021-02-25 — — US disclosed
US-8444450-B2 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. (JP) 2013-05-21 — — US disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 — — US disclosed
EP-1637570-B1 Color-memorizing photochromic writing instrument PILOT INK CO LTD (JP) 2007-06-27 — — EP disclosed
CN-1315555-C Method of alternatively dioplaying photochromic action of memory color in toy assembly, and photochromic toy having alternatively color memory PILOT INK CO LTD (JP) 2007-05-16 — — CN disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 — — US disclosed
EP-1637570-A1 Color-memorizing photochromic writing instrument THE PILOT INK CO., LTD. (JP) 2006-03-22 — — EP disclosed
US-20060053975-A1 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. 2006-03-16 — — US disclosed
EP-1415692-B1 Method of changing color of a toy and colour changing toy PILOT INK CO LTD (JP) 2005-05-04 — — EP disclosed
US-20040135097-A1 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. 2004-07-15 — — US disclosed
CN-1498666-A Method of alternatively dioplaying photochromic action of memory color in toy assembly, and photochromic toy having alternatively color memory ��ī�����˹��ʽ���� 2004-05-26 — — CN disclosed
EP-1415692-A1 Method of changing color of a toy and colour changing toy THE PILOT INK CO., LTD. (JP) 2004-05-06 — — EP disclosed
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