Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.76 |
| ▸ | CA4 | P22748 | 1/20 | 0.76 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | CES1 | P23141 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 10/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11789341 | 0.89 | CA2 (0.94) | CA2CA4USP2CES2CES1 | |
| Benzoic Acid SCHEMBL158696 | 0.87 | CA2 (0.80) | CA2CA4USP2CES2CES1 | |
| Benzoic Acid SCHEMBL28337190 | 0.87 | CA2 (0.80) | CA2CA4USP2CES2CES1 | |
| Benzoic Acid SCHEMBL27345977 | 0.87 | CA2 (0.90) | CA2CA4USP2CES2CES1 | |
| Benzoic Acid SCHEMBL11740323 | 0.87 | CA2 (0.80) | CA2CA4USP2CES2CES1 | |
| Benzoic Acid SCHEMBL29624 | 0.87 | CA2 (0.89) | CA2CA4USP2CES2CES1 | |
| Benzoic Acid SCHEMBL944537 | 0.87 | CA2 (0.89) | CA2CA4USP2CES2CES1 | |
| Benzoic Acid SCHEMBL1798863 | 0.87 | CA2 (0.89) | CA2CA4USP2CES2CES1 | |
| Benzoic Acid SCHEMBL20570059 | 0.87 | CA2 (0.89) | CA2CA4USP2CES2CES1 | |
| Benzoic Acid SCHEMBL20570232 | 0.87 | CA2 (0.89) | CA2CA4USP2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240043609-A1 | NOVEL THERMOPLASTIC POLYESTERS AND SYNTHESIS THEREFOR | EASTMAN CHEMICAL COMPANY (US) | 2024-02-08 | — | — | US | disclosed |
| EP-4263662-A1 | NOVEL THERMOPLASTIC POLYESTERS AND SYNTHESIS THEREFOR | Eastman Chemical Company (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-116745339-A | Novel thermoplastic polyesters and their synthesis | 伊士曼化工公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022133001-A1 | NOVEL THERMOPLASTIC POLYESTERS AND SYNTHESIS THEREFOR | EASTMAN CHEMICAL COMPANY (US) | 2022-06-23 | — | — | WO | disclosed |
| CN-109563252-B | Polyester compositions comprising tetramethylcyclobutanediol and ethylene glycol using an improved catalyst system | 伊士曼化工公司 | 2022-04-26 | — | — | CN | disclosed |
| US-11072684-B2 | Polyester compositions which comprise tetramethylcyclobutandiol and ethylene glycol, with improved catalyst system | EASTMAN CHEMICAL COMPANY (US) | 2021-07-27 | — | — | US | disclosed |
| EP-3500616-B1 | POLYESTER COMPOSITIONS WHICH COMPRISE TETRAMETHYLCYCLOBUTANDIOL AND ETHYLENE GLYCOL, WITH IMPROVED CATALYST SYSTEM | EASTMAN CHEM CO (US) | 2021-03-24 | — | — | EP | disclosed |
| US-20200165379-A1 | POLYESTER COMPOSITIONS WHICH COMPRISE TETRAMETHYLCYCLOBUTANDIOL AND ETHYLENE GLYCOL, WITH IMPROVED CATALYST SYSTEM | EASTMAN CHEMICAL COMPANY (US) | 2020-05-28 | — | — | US | disclosed |
| EP-3500616-A1 | POLYESTER COMPOSITIONS WHICH COMPRISE TETRAMETHYLCYCLOBUTANDIOL AND ETHYLENE GLYCOL, WITH IMPROVED CATALYST SYSTEM | Eastman Chemical Company (US) | 2019-06-26 | — | — | EP | disclosed |
| EP-2912095-B1 | COPOLYESTERS CONTAINING NEOPENTYL GLYCOL AND 2,2,4,4-TETRAALKYL-1,3-CYCLOBUTANEDIOL | EASTMAN CHEM CO (US) | 2018-11-14 | — | — | EP | disclosed |
| EP-1004624-A1 | Latent mercaptan stabilizers for improved weatherability of clear halogen-containing polymer compositions | MORTON INTERNATIONAL, INC. (US) | 2000-05-31 | — | — | EP | disclosed |
| US-5786399-A | PVC foam compositions | MORTON INTERNATIONAL, INC. (US) | 1998-07-28 | — | — | US | disclosed |
| EP-0850987-A1 | Improved PVC foam compositions | MORTON INTERNATIONAL, INC. (US) | 1998-07-01 | — | — | EP | disclosed |
| US-5753719-A | ACTIVATOR FOR BLOWING AGENTS | MORTON INTERNATIONAL, INC. (US) | 1998-05-19 | — | — | US | disclosed |
| US-5726213-A | FOAMING VINYL CHLORIDE POLYMER BY HEATING MIXTURE OF POLYMER, BLOWING AGENT, STABILIZER INCLUDING ORGANOTIN MERCAPTIDE OF MERCAPTOALKYL CARBOXYLATE OR SULFIDE THEREOF, OPTIONAL ORGANOTIN SALT | MORTON INTERNATIONAL, INC. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5239020-A | Polyesters from terephthalic and/or isophthalic acids and 1,4-butanediol and/or 1,4-cyclohexanedimethanol blended with bisphenol a polycarbonates, transparent, nearly colorless | EASTMAN KODAK COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0233917-B1 | POLYESTER/POLYCARBONATE BLENDS | EASTMAN KODAK COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |
| EP-0233917-A1 | POLYESTER/POLYCARBONATE BLENDS. | EASTMAN KODAK CO (US) | 1987-09-02 | — | — | EP | disclosed |
| WO-1987001122-A1 | POLYESTER/POLYCARBONATE BLENDS | EASTMAN KODAK COMPANY (US) | 1987-02-26 | — | — | WO | disclosed |
| US-4173692-A | ORGANIC ALKALI METAL SALT AND ORGANOTIN COMPOUND AS CATALYST | M&T CHEMICALS INC. (US) | 1979-11-06 | — | — | US | disclosed |